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ORIGINAL RESEARCH article

Front. Neurol.
Sec. Endovascular and Interventional Neurology
Volume 15 - 2024 | doi: 10.3389/fneur.2024.1442979
This article is part of the Research Topic Imaging Selection and Treatments for Posterior Circulation Large Vessel Occlusion View all articles

The predictive value of admission blood glucose to serum albumin ratio for futile recanalization after successful interventional recanalization in acute cerebral infarction with large vessel occlusion

Provisionally accepted
Wensheng Zhang Wensheng Zhang 1,2Jie Li Jie Li 1Hongxing Zhou Hongxing Zhou 1Weifang Xing Weifang Xing 2Kaifeng Li Kaifeng Li 1Yudi Li Yudi Li 1Jinzhao He Jinzhao He 2Xiongjun He Xiongjun He 1Liu Yajie Liu Yajie 1Li Ling Li Ling 1*
  • 1 Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong Province, China
  • 2 Heyuan People's Hospital, Heyuan, China

The final, formatted version of the article will be published soon.

    Aims: We aim to explore the predictive value of admission blood glucose to serum albumin ratio (AAR) for futile recanalization after successful interventional recanalization of acute cerebral infarction. Methods: We retrospectively collected the data of patients suffered from acute cerebral infarction due ro anterior circulation large vessel occlusion and received successful interventional recanalization from January 2019 to November 2023. Statistical analysis of clinical data was conducted using SPSS 26.0. Results: A total of 452 patients were included in the study. There were statistically significant differences in mRS score and futile recanalization rates among the three groups of patients at 3 months after surgery according to AAR tertile. In the multiple logistic regression analysis, there were statistically significant differences in Diabetes, grade of NIHSS score at admission, AAR tertiles, good collateral circulation and Pathogenesis. The Receiver Operating Characteristic curve (ROC) curve of AAR predicting futile recanalization was drawn with an AUC of 0.582 and a 95% confidence interval of 0.529-0.634. After combining grade of NIHSS score at admission, AAR tertiles and good collateral circulation, a ROC curve was drawn to predict futile recanalization, with an AUC of 0.907 and a 95% confidence interval of 0.879-0.936. Conclusion: AAR is a new composite indicator for predicting futile recanalization in patients with acute cerebral infarction with anterior circulation large vessel occlusion. The combination of grade of NIHSS score at admission, AAR tertiles and good collateral circulation has a high predictive power for futile recanalization.

    Keywords: Admission blood glucose to serum albumin ratio, Large vessel occlusion, Acute cerebral infarction, Interventional recanalization, futile recanalization

    Received: 05 Aug 2024; Accepted: 09 Dec 2024.

    Copyright: © 2024 Zhang, Li, Zhou, Xing, Li, Li, He, He, Yajie and Ling. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Li Ling, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong Province, China

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