This article is a correction to:
Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization
Lara-Jasmin Schröder1,2†
Hauke Thiesler3†
Lina Gretenkort3
Thiemo Malte Möllenkamp1
Martin Stangel2,4
Viktoria Gudi1‡
Herbert Hildebrandt2,3*‡- 1Clinic for Neurology, Hannover Medical School, Hannover, Germany
- 2Center for Systems Neuroscience Hannover, Hannover, Germany
- 3Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany
- 4Translational Medicine, Novartis Institute for Biomedical Research, Novartis, Basel, Switzerland
A corrigendum on
Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization
by Schröder, L.-J., Thiesler, H., Gretenkort, L., Möllenkamp, T. M., Stangel, M., Gudi, V., and Hildebrandt, H. (2023). Front. Cell. Neurosci. 17:1207540. doi: 10.3389/fncel.2023.1207540
In the published article, there was an error in Figure 6 as published. In panel A, the micrographs in columns 2 and 3 were labeled incorrectly. The corrected Figure 6 and its caption appear below.
FIGURE 6
Figure 6. PolySia DP24–30 has no direct impact on OPC differentiation. (A) Representative images of primary rat OPC cultures stained for A2B5 (magenta) and GALC (green) after 2 days of in vitro differentiation in the presence of polySia DP8–14 or polySia DP24–30, as indicated. Nuclear counterstain with DAPI (blue). Scale bars, 50 μm. (B–D) Absolute cell numbers per frame (B), and relative numbers of A2B5 (C) or GALC-positive cells (D). Data represent individual values and means ± SEM of n = 9–11 independent OPC cultures per condition. OPCs were obtained from overall three OPC pools prepared from eight neonatal rats, each. Per OPC culture well, 15–20 frames (150 × 200 μm) were evaluated. The one-way-ANOVA revealed significant differences (P < 0.0001 for GALC; P = 0.0223 for A2B5), and Tukey's post hoc tests were applied. Significant group differences are indicated (*P < 0.05; ****P < 0.0001).
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: multiple sclerosis, organotypic cerebellar slice culture, remyelination, polysialic acid (polySia), Siglec-E, microglia, neuroinflammation, immunomodulation
Citation: Schröder L-J, Thiesler H, Gretenkort L, Möllenkamp TM, Stangel M, Gudi V and Hildebrandt H (2023) Corrigendum: Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization. Front. Cell. Neurosci. 17:1275048. doi: 10.3389/fncel.2023.1275048
Received: 09 August 2023; Accepted: 11 August 2023;
Published: 23 August 2023.
Edited and reviewed by: Shirin Hosseini, Technical University of Braunschweig, Germany
Copyright © 2023 Schröder, Thiesler, Gretenkort, Möllenkamp, Stangel, Gudi and Hildebrandt. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Herbert Hildebrandt, hildebrandt.herbert@mh-hannover.de
†These authors have contributed equally to this work and share first authorship
‡These authors have contributed equally to this work and share last authorship