Current Knowledge on the Function of α-Methyl Acyl-CoA Racemase in Human Diseases
- 1Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, South Korea
- 2Department of Medical Science, Metabolic Syndrome and Cell Signaling Laboratory, Institute for Cancer Research, College of Medicine, Chungnam National University, Daejeon, South Korea
- 3Department of Life Science, Hyehwa Liberal Arts College, LINC Plus Project Group, Daejeon University, Daejeon, South Korea
- 4College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea
- 5Department of Neurosurgery, Institute for Cancer Research, College of Medicine, Chungnam National University, Daejeon, South Korea
A corrigendum on
Current Knowledge on the Function of α-Methyl Acyl-CoA Racemase in Human Diseases
by Kong, G., Lee, H., Tran, Q., Kim, C., Park, J., Kwon, S., Kim, S.-H., Park, J. Front. Mol. Biosci. 7:153. doi:10.3389/fmolb.2020.00153
In the original article, there was a mistake in Figure 2 as published. The cholesterol structure should be the chiral for omega oxidation, instead of the chiral structure used in the figure; as both groups are methyl, we mentioned the oxidation of omega by adding CH2OH to carbon 15 to create a chiral center. The corrected Figure 2 appears below.
FIGURE 2. Illustration for the oxidation step of (3R)- and (3S)-phytanic acid as resulting from normal diet and (25R)-trihydroxy cofluorocarbonate (THCA) biosynthesized from liver-derived cholesterol.
Furthermore, in the original article, there was a mistake in the legend for Figure 6 as published. In the thioester part of the AMACR structure, the keto group was mistakenly omitted. The correct Figure 6 and legend appear below.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: AMACR, branched-chain fatty acid, cancer development, B-oxidation, lipid metabolism
Citation: Kong G, Lee H, Tran Q, Kim C, Park J, Kwon SH, Kim S-H and Park J (2021) Corrigendum: Current Knowledge on the Function of α-Methyl Acyl-CoA Racemase in Human Diseases. Front. Mol. Biosci. 8:639164. doi: 10.3389/fmolb.2021.639164
Received: 08 December 2020; Accepted: 22 January 2021;
Published: 25 March 2021.
Edited and reviewed by:
Yong Teng, Augusta University, Augusta, GA, United StatesCopyright © 2021 Kong, Lee, Tran, Kim, Park, Kwon, Kim and Park. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Seon-Hwan Kim, neons@cnu.ac.kr; Jongsun Park, insulin@cnu.ac.kr