This article is a correction to:
A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii
Sung-Pang Chen1,2
Eric H-L Chen1
Sheng-Yung Yang1
Pin-Shin Kuo1,2
Hau-Ming Jan1
Tsai-Chen Yang1
Ming-Yen Hsieh1
Kung-Ta Lee3
Chun-Hung Lin1,2
Rita P-Y Chen1,2*- 1Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
- 2Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan
- 3Department of Biochemical Science and Technology, National Taiwan University, Taipei, Taiwan
by Chen, S.-P., Chen, E. H.-L., Yang, S.-Y., Kuo, P.-S., Jan, H.-M., Yang, T.-C., Hsieh, M.-Y., Lee, K.-T., Lin, C.-H., and Chen, R. P.-Y. (2021). Front. Microbiol. 12:678330. doi: 10.3389/fmicb.2021.678330
In the original article, there was an error. “Gram(–) bacteria” was written where “Gram(+) bacteria” should have been used.
A correction has been made to Results, Antimicrobial Activity is Related to the Lipid Composition of Pathogens, paragraph 1:
“Unlike polymyxins, our peptide could kill Gram(+) bacteria such as Staphylococcus aureus and Staphylococcus epidermidis (Supplementary Figure 2), suggesting that our peptides do not function via LPS binding. When testing other Gram(+) bacteria, we noticed that our peptides were not effective against Enterococcus faecalis at the concentrations used (32 μg/mL and lower). To examine whether the discrimination comes from the bacterial membrane differences, the membrane lipids of these two bacteria were extracted by methanol and chloroform, and TLC was used to analyze the lipid composition (Supplementary Figure 3). The data showed that E. faecalis had much lower contents of phosphatidylethanolamine (PE) and phosphatidylserine (PS) than A. baumannii (Figure 5).”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: antimicrobial peptide, antibiotic-resistant, Acinetobacter baumannii, lipid, membrane, drug-resistant
Citation: Chen S-P, Chen EH-L, Yang S-Y, Kuo P-S, Jan H-M, Yang T-C, Hsieh M-Y, Lee K-T, Lin C-H and Chen RP-Y (2022) Corrigendum: A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii. Front. Microbiol. 12:821347. doi: 10.3389/fmicb.2021.821347
Received: 24 November 2021; Accepted: 27 December 2021;
Published: 14 January 2022.
Edited and reviewed by: Rustam Aminov, University of Aberdeen, United Kingdom
Copyright © 2022 Chen, Chen, Yang, Kuo, Jan, Yang, Hsieh, Lee, Lin and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Rita P-Y Chen, pyc@gate.sinica.edu.tw