Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo
- 1Department of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yong-In, South Korea
- 2The Bacteriophage Bank of Korea, Hankuk University of Foreign Studies, Yong-In, South Korea
- 3Samsung Medical Center, Sungkyukwan University School of Medicine, Suwon, South Korea
by Cha, K., Oh, H. K., Jang, J. Y., Jo, Y., Kim, W. K., Ha, G. U., Ko, K. S., and Myung, H. (2018). Front. Microbiol. 9:696. doi: 10.3389/fmicb.2018.00696
In the original article, there was an error. We mistakenly misspelled histamine as “histamin” in a heading in the Materials and Methods section. A correction has been made to Materials and Methods, where the heading Cytokine, IgE, and Histamine Assays now appears correctly.
In the original article, there was an error. We mistakenly omitted the statement “No significant change in histamine level was observed when phage cocktail was administered (Supplementary Figure 1).” in the Results section.
Supplementary Figure 1. Histamine levels in sera from mice treated with phages using three different routes, intraperitoneal (i.p), intranasal (i.n), or oral (p.o). The experiment was performed in triplicate. *P < 0.05, **P < 0.01.
A correction has been made to Results, Immune Reactions Against the Phage Cocktail, paragraph 1:
“Phages are foreign substances to mice and there are chances they could elicit immune responses. We checked changes in serum IgE level indicating any allergic responses for three different routes of phage injection (Figure 7A). A 20% increase in serum IgE was observed for intraperitoneal injection route, while no significant change was observed for either intranasal or oral administration. For cytokines, a slight increase of serum GM-CSF was observed for all three routes of phage administration (Figure 7B). In intraperitoneal route, slight increases of IL2, IL10, and IL17A were also observed. Thus, inflammatory response against the phage cocktail was minimal. No significant change in histamine level was observed when phage cocktail was administered (Supplementary Figure 1).”
Accordingly, the added Supplementary Figure 1 appears below.
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated and Supplementary Figure 1 is now included.
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Keywords: multidrug-resistance, Acinetobacter baumannii, bacteriophage therapy, mouse model, genome analysis
Citation: Cha K, Oh HK, Jang JY, Jo Y, Kim WK, Ha GU, Ko KS and Myung H (2022) Corrigendum: Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in vivo. Front. Microbiol. 12:815173. doi: 10.3389/fmicb.2021.815173
Received: 15 November 2021; Accepted: 29 November 2021;
Published: 05 January 2022.
Edited by:
Rustam Aminov, University of Aberdeen, United KingdomReviewed by:
Andrzej Gorski, Polish Academy of Sciences (PAN), PolandCopyright © 2022 Cha, Oh, Jang, Jo, Kim, Ha, Ko and Myung. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Heejoon Myung, aGpteXVuZyYjeDAwMDQwO2h1ZnMuYWMua3I=