Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line
- 1Centre National de la Recherche Scientifique UMR 9019, B Cell and Genome Plasticity Team, Villejuif, France
- 2Gustave Roussy, Villejuif, France
- 3Université Paris-Saclay, Orsay, France
- 4Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
- 5Sorbonne Université, Paris, France
By Lerner LK, Bonte D, Le Guillou M, Mohammad MM, Kasraian Z, Sarasin A, Despras E and Aoufouchi S (2022). Front. Immunol. 13:871766. doi: 10.3389/fimmu.2022.871766
In the published article, there was an error in Figure 5 as published. The published version contains typing errors. The corrected Figure 5 and its caption appear below.
Figure 5 Distribution of point-mutations along the amplified Ramos VH region. Independently occurring base substitutions are indicated at each nucleotide position. The POLH hotspots (WA/TW) targeted following the expression of mUb-PCNA are in indicated in red. The figure represent the pool of base substitution obtained from the clones indicated in Table 2A. The Nucleotide Substitutions in blue indicated above the Ramos VH sequence are from the 5 clones expressing mUb-PCNA and those below in green are from the five control clones.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: immunoglobulin somatic hypermutation, PCNA monoubiquitination, Ramos B cell line, USP1 inhibition, A/T mutation pathway
Citation: Lerner LK, Bonte D, Le Guillou M, Mohammad MM, Kasraian Z, Sarasin A, Despras E and Aoufouchi S (2024) Corrigendum: Expression of constitutive fusion of ubiquitin to PCNA restores the level of immunoglobulin A/T mutations during somatic hypermutation in the Ramos cell line. Front. Immunol. 15:1419493. doi: 10.3389/fimmu.2024.1419493
Received: 18 April 2024; Accepted: 14 May 2024;
Published: 22 May 2024.
Edited and Reviewed by:
Francesca Granucci, University of Milano-Bicocca, ItalyCopyright © 2024 Lerner, Bonte, Le Guillou, Mohammad, Kasraian, Sarasin, Despras and Aoufouchi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Said Aoufouchi, said.aoufouchi@gustaveroussy.fr
†Present address: Leticia K. Lerner, Cell Death and Drug Resistance in Hematological Disorders Team, Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, Paris, France Emmanuelle Despras, Sorbonne Université, INSERM UMRS 938, Équipe Instabilité des Microsatellites et Cancer, Centre de recherche Saint Antoine, Paris, France
‡These authors have contributed equally to this work and share first authorship