Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations

Wong, Mabel T. Y.; Kelm, Sebastian; Liu, Xiaofeng; Taylor, Richard D.; Baker, Terry; Essex, Jonathan W.

doi:10.3389/fimmu.2022.969176

CORRECTION article

Front. Immunol., 04 July 2022

Sec. B Cell Biology

Volume 13 - 2022 | https://doi.org/10.3389/fimmu.2022.969176

Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations

This article is a correction to:

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations
1. Read original article

Mabel T. Y. Wong¹

Sebastian Kelm²

Xiaofeng Liu²

Richard D. Taylor²

Terry Baker^2†

Jonathan W. Essex^1*

¹School of Chemistry, University of Southampton, Southampton, United Kingdom
²UCB, Slough, United Kingdom

A Corrigendum on:
Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations.

Wong MTY, Kelm S, Liu X, Taylor RD, Baker T and Essex JW (2022) Front. Immunol. 13:884110. doi: 10.3389/fimmu.2022.884110

In the original article, there was an error in affiliations 2 and 3. Instead of “Computer Aided Drug Design, Union Chimique Belge (UCB) Celltech, Slough, United Kingdom” and “Structural Biology, Union Chimique Belge (UCB) Celltech, Slough, United Kingdom”, respectively, they should both be corrected to “UCB, Slough, United Kingdom”.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: antibody-antigen interactions, antibody binding, antibody affinity, antibody interface hydration, CDR flexibility, molecular dynamics, replica exchange

Citation: Wong MTY, Kelm S, Liu X, Taylor RD, Baker T and Essex JW (2022) Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations. Front. Immunol. 13:969176. doi: 10.3389/fimmu.2022.969176

Received: 14 June 2022; Accepted: 15 June 2022;
Published: 04 July 2022.

Approved by:

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2022 Wong, Kelm, Liu, Taylor, Baker and Essex. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Jonathan W. Essex, ai53LmVzc2V4QHNvdG9uLmFjLnVr

^†Deceased

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.