Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine
- 1Turku PET Centre, University of Turku, Turku, Finland
- 2Turku Center for Disease Modeling, University of Turku, Turku, Finland
- 3A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
- 4Turku PET Centre, Turku University Hospital, Turku, Finland
- 5InFLAMES Research Flagship Center, University of Turku, Turku, Finland
- 6Heart Center, Turku University Hospital and University of Turku, Turku, Finland
A Corrigendum on
Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine
By Palani S, Miner MWG, Virta J, Liljenbäck H, Eskola O, Örd T, Ravindran A, Kaikkonen MU, Knuuti J, Li X-G, Saraste A and Roivainen A (2022) Front. Immunol. 13:821423. doi: 10.3389/fimmu.2022.821423
In the original article, there was a mistake in Figure 2 as published. The Mac-3 and SLC7A7 images on the left column were incorrectly positioned, i.e they had changed places. The corrected Figure 2 appears below.
Figure 2 Expression of Mac-3 and glutamine transporters by mouse aortic plaque macrophages. Movat’s pentachrome staining of the aortic root demonstrates that atherosclerotic plaques were composed mostly of a fibrous cap and a necrotic region. Immunostaining of adjacent sections shows that Mac-3-positive macrophages are also positive for glutamine transporters SLC1A5, SLC3A2, and SLC7A7. Higher magnifications of the valve and plaque vessel regions are shown in the black and red rectangular boxes, respectively. Expression of SLC1A5 is prominent in the aortic valve region but not in the vessel plaque region. Expression of SLC3A2 is absent from the valve region but present in the vessel plaque region. Expression of SLC7A7 is clear in both the valve and vessel plaque regions. Scale bar = 200 μm; zoomed region scale bar = 50 μm.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: atherosclerosis, 18F-fluoroglutamine, PET/CT, macrophages, inflammation
Citation: Palani S, Miner MWG, Virta J, Liljenbäck H, Eskola O, Örd T, Ravindran A, Kaikkonen MU, Knuuti J, Li X-G, Saraste A and Roivainen A (2022) Corrigendum: Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-18F-Fluoroglutamine. Front. Immunol. 13:902544. doi: 10.3389/fimmu.2022.902544
Received: 23 March 2022; Accepted: 28 March 2022;
Published: 12 April 2022.
Edited and reviewed by:
Nick Devoogdt, Free University of Brussels, BelgiumCopyright © 2022 Palani, Miner, Virta, Liljenbäck, Eskola, Örd, Ravindran, Kaikkonen, Knuuti, Li, Saraste and Roivainen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Anne Roivainen, anne.roivainen@utu.fi; Senthil Palani, palsen@utu.fi