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CORRECTION article

Front. Immunol., 06 December 2021
Sec. Viral Immunology
Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.808068
This article is part of the Research Topic Humanized Mouse Models to Study Immune Responses to Human Infectious Organisms View all 11 articles

Corrigendum: Humanized Mice for the Evaluation of Novel HIV-1 Therapies

This article is a correction to:

  1. Humanized Mice for the Evaluation of Novel HIV-1 Therapies

    1. Read original article
Shawn Abeynaike,Shawn Abeynaike1,2Silke Paust,*Silke Paust1,2*
  • 1Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States
  • 2The Skaggs Graduate Program in Chemical and Biological Sciences, The Scripps Research Institute, La Jolla, CA, United States

A Corrigendum on:
Humanized Mice for the Evaluation of Novel HIV-1 Therapies

By Abeynaike S and Paust S (2021). Front. Immunol. 12:636775. doi: 10.3389/fimmu.2021.636775

In the original article, there was a mistake in Table 1 as published. The authors incorrectly categorized thy/liv implanted SCID-hu mice as showing no multilineage hematopoeisis. To clarify, Namikawa 1990, showed that SCID mice implanted with both Thy/Liv displayed multilineage hematopoiesis. Specifically, they showed in addition to T cells (CD3, CD4 and CD8), the presence of mature and immature forms of myelomonocytic cells which stained positive for human CD15, as well as progenitors for erythroids and megakaryocytic lineages (1).

TABLE 1
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Table 1 Summary of humanized mouse models and their tissue-based chimerism.

The corrected Table 1 appears below.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Reference

1. Namikawa R, Weilbaecher K, Kaneshima H, Yee E, Mccune J. Long-Term Human Hematopoiesis in the SCID-hu Mouse. J Exp Med (1990) 172(4):1055–63.

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Keywords: humanized mice, BLT, DRAG, HIV-1 infection, viral latency, latency reversal, immunotherapy, gene therapy

Citation: Abeynaike S and Paust S (2021) Corrigendum: Humanized Mice for the Evaluation of Novel HIV-1 Therapies. Front. Immunol. 12:808068. doi: 10.3389/fimmu.2021.808068

Received: 03 November 2021; Accepted: 08 November 2021;
Published: 06 December 2021.

Edited and reviewed by:

Qingfeng Chen, Institute of Molecular and Cell Biology (A*STAR), Singapore

Copyright © 2021 Abeynaike and Paust. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Silke Paust, paust@scripps.edu

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.