This article is a correction to:
Corticosteroids for Treating Sepsis in Adult Patients: A Systematic Review and Meta-Analysis
Huoyan Liang1,2†Heng Song1,2†
Ruiqing Zhai3Gaofei Song1,2Hongyi Li1,2
Xianfei Ding1Quancheng Kan4*
Tongwen Sun1,2*- 1General ICU, The First Affiliated Hospital of Zhengzhou University, Henan Key Laboratory of Critical Care Medicine, Zhengzhou Key Laboratory of Sepsis, Henan Engineering Research Center for Critical Care Medicine, Zhengzhou, China
- 2Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China
- 3College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China
- 4Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
A Corrigendum on:
Corticosteroids for Treating Sepsis in Adult Patients: A Systematic Review and Meta-Analysis
By Liang H, Song H, Zhai R, Song G, Li H, Ding X, Kan Q and Sun T (2021). Front. Immunol. 12:709155. doi: 10.3389/fimmu.2021.709155
In the original article, there was a mistake in Figure 2, Supplemental Figures 40-41, 43, 45-46 and Table 2 as published. For Figure 2, we mistakenly adopted the fixed effect model, resulting in the difference between the picture and the actual results. In practice, we need to use the random-effect model to calculate the effect quantity and its 95% CIs, which is the most reasonable. In both the method part and the result part, we describe the calculation using the random effect model. For Supplemental Figures 40-41, 43, 45-46 and Table 2, as we reworked all the figures, we made mistakes in uploading in the revised manuscript. The corrected Figure 2, Supplemental Figures 40-41, 43, 45-46 and Table 2 appear below.
FIGURE 2
Figure 2 The 28-day mortality of patients with sepsis based on the corticosteroids treatment. The pooled effects in the forest plot were calculated by the M-H method with the random-effects model.
TABLE 2
Table 2 The findings and evidence rank of the included studies in patients with sepsis.
In the original article, there was an error. As the outcomes for Hypernatremia, Hyperglycemia and SOFA at day 7 were revised several times, and the pooled effects were not changed, but the up or low 95% CI had a little change. When we modified, we ignored the modifications in the two places.
A correction has been made to RESULTS, Secondary Outcomes of RESULTS, Paragraph 1:
“Supplementary Figures 10–22 present the assessment of the secondary outcomes. Corticosteroids achieved a small reduction in length of stay in hospital (MD, −1.38; 95% CI, −2.28 to −0.49; I2 = 5%; evidence rank, high), SOFA scores at day 7 (MD, −0.90; 95% CI, −1.72 to −0.09; I2 = 93%; evidence rank, low), and time to resolution of shock (MD, −1.35; 95% CI, −1.79 to −0.92; I2 = 68%; evidence rank, low) for patients with sepsis. Conversely, corticosteroids resulted in higher risk of hypernatremia (RR, 1.51; 95% CI, 1.10–2.07; I2 = 0%; evidence rank, moderate) and hyperglycemia (RR, 1.19; 95% CI, 1.10–1.29; I2 = 49%; evidence rank, high).”
The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.
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Supplementary Material
The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fimmu.2021.771779/full#supplementary-material
Keywords: corticosteroids, sepsis, mortality, systematic review, meta-analysis
Citation: Liang H, Song H, Zhai R, Song G, Li H, Ding X, Kan Q and Sun T (2021) Corrigendum: Corticosteroids for Treating Sepsis in Adult Patients: A Systematic Review and Meta-Analysis. Front. Immunol. 12:771779. doi: 10.3389/fimmu.2021.771779
Received: 07 September 2021; Accepted: 25 October 2021;
Published: 05 November 2021.
Edited and reviewed by:
Pietro Ghezzi, Brighton and Sussex Medical School, United KingdomCopyright © 2021 Liang, Song, Zhai, Song, Li, Ding, Kan and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Tongwen Sun, suntongwen@163.com; Quancheng Kan, kanquancheng@126.com
†These authors have contributed equally to this work