This article is a correction to:
Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren’s Syndrome
Ning Li1†
Lei Li2†Mengyao Wu1†
Yusi Li1Jie Yang3Yicheng Wu3Haimin Xu2
Danyang Luo1Yiming Gao1*Xiaochun Fei2*
Liting Jiang1*- 1Department of Stomatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, Shanghai, China
- 2Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- 3Core Facility of Basic Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
A Corrigendum on:
Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren’s Syndrome
byLi N, Li L, Wu M, Li Y, Yang J, Wu Y, Xu H, Luo D, Gao Y, Fei X and Jiang L (2021). Front. Immunol. 12:697157. doi: 10.3389/fimmu.2021.697157
In the original article, there was a mistake in the legends for Figures 7, Figure 8 as published. The authors confused the concept of scanning electron micrographs (SEM) and Transmission electron micrographs (TEM). The correct legend appears below.
Figure 7: Representative transmission electron micrograph (TEM) images of acinar-specific ultrastructure changes in the labial salivary gland of non-pSS and pSS. In non-pSS (Grade II), the structure of the acinar is normal, and the glandular epithelial cells in the acinar are myoepithelial cells. The cytoplasmic skeletal components and their unique myofilaments could be seen. With the aggravation of pSS, there is serous and mucous acini atrophy, glandular epithelial cell nucleus shrinkage, organelle swelling to varying degrees, and increase of interstitial collagen components. MD, Mucous Droplets; N, Nucleus; MC, myoepithelial cell; C, collagen; LD, lipid droplets. Bar: 5 μm, 1 μm, 500 nm.
Figure 8: Representative transmission electron micrograph (TEM) images of dust-specific ultrastructure changes in the labial salivary gland of non-pSS and pSS. In non-pSS (Grade II), the duct structure of normal glands is clear, and ductal epithelial cells have full nuclei and are connected with myoepithelial cells by desmosomes. As the degree of SS disease increases, duct structures begin to atrophy and become disordered, and part of the basement membrane damage disappears. Ductal epithelial cells can see obvious nuclear pyknosis, fat infiltration in the cytoplasm, and swelling of intracytoplasmic organelles. MC, myoepithelial cell; DN, Ductal Epithelial Cells Nucleus; De, desmosome. Bar, 5 μm, 1 μm, 500 nm.**
In the original article, there was an error. The authors confused the concept of scanning electron micrographs (SEM) and Transmission electron micrographs (TEM).
Corrections of “scanning electron micrographs (SEM)” to “transmission electron micrographs (TEM)” have been made in the following parts: Abstract, Methods; Introduction, paragraph 4; Materials and Methods, Clinical Samples; and Discussion, paragraph 3. In addition, Materials and Methods, Scanning Electron Micrographs (SEM) has been changed to Transmission electron micrographs (TEM):
“All non-SS and pSS labial salivary glands samples for transmission electron microscopy were subjected to 2.5% glutaraldehyde fixation, 1% osmium tetroxide postfixation, and ethanol gradient dehydration. Two changes of 100% propylene oxido (P.O.) for 10 minutes each and finally into the embedding resin. The samples were sectioned by diamond knife (LEICA EM UC7) to 70-90nm, followed by electron stained with lead citrate, and visualized on a Transmission electron microscope (HITACHI H-7650).”
The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: primary Sjogren’s syndrome (pSS), transcriptome sequencing, potential biomarkers, bioinformatics analysis, severity
Citation: Li N, Li L, Wu M, Li Y, Yang J, Wu Y, Xu H, Luo D, Gao Y, Fei X and Jiang L (2021) Corrigendum: Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren’s Syndrome. Front. Immunol. 12:759203. doi: 10.3389/fimmu.2021.759203
Received: 16 August 2021; Accepted: 13 September 2021;
Published: 29 September 2021.
Edited and reviewed by:
Kristi A. Koelsch, University of Oklahoma Health Sciences Center, United StatesCopyright © 2021 Li, Li, Wu, Li, Yang, Wu, Xu, Luo, Gao, Fei and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Yiming Gao, ZHJnYW95bUAxNjMuY29t; Xiaochun Fei, eGNmMDIyMkAxNjMuY29t; Liting Jiang, ZHJqaWFuZ2xpdGluZ0AxNjMuY29t
†These authors have contributed equally to this work and share first authorship