IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimulation
- 1Gansu Provincial Key Laboratory of Evidence Based Medicine and Clinical Translation and Lanzhou Center for Tuberculosis Research, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China
- 2School of Basic Medical Sciences, Institute of Pathogen Biology, Lanzhou University, Lanzhou, China
- 3Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States
- 4Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States
- 5Center of Life Science, School of Life Sciences, Lanzhou University, Lanzhou, China
A Corrigendum on
IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimulation
by Liu, X., Li, F., Niu, H., Ma, L., Chen, J., Zhang, Y., et al. (2019). Front. Immunol. 10:2350. doi: 10.3389/fimmu.2019.02350
In the original article, there was a mistake in Figure 3 as published. In Figure 3A some panels were accidentally duplicated. The corrected Figure 3 appears below.
Figure 3. Persistent M. tuberculosis antigen MH plus LT70 (ML) stimulation decreased the number of TB10.44−12 pentamer-positive CD8+ T cells. The antigen immunized mice were stimulated with BCG 3 days before the immunodetection point. Spleen lymphocytes were isolated and the numbers of TB10.4 pentamer-positive CD8+ T cells were detected. (A) The flow cytometric analysis of TB10.44−12 pentamer specific spleen CD8+ T cells from persistent ML stimulated mice, a representative experiment. (B) The percentage of TB10.44−12 pentamer-positive T cells among spleen CD8+ T lymphocytes from persistent ML stimulated mice, mean ± SEM. n = 4–6, *p < 0.05.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: Mycobacterium tuberculosis, T cell exhaustion, T cell dysfunction, antigen persistence, IL-2
Citation: Liu X, Li F, Niu H, Ma L, Chen J, Zhang Y, Peng L, Gan C, Ma X and Zhu B (2020) Corrigendum: IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimulation. Front. Immunol. 11:1671. doi: 10.3389/fimmu.2020.01671
Received: 29 May 2020; Accepted: 22 June 2020;
Published: 31 July 2020.
Edited and reviewed by: Denise L. Doolan, James Cook University, Australia
Copyright © 2020 Liu, Li, Niu, Ma, Chen, Zhang, Peng, Gan, Ma and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Bingdong Zhu, bdzhu@lzu.edu.cn
†These authors have contributed equally to this work