This article is a correction to:
Reconstruction and Analysis of the lncRNA-miRNA-mRNA Network Based on Competitive Endogenous RNA Reveal Functional lncRNAs in Dilated Cardiomyopathy
Lichan Tao
Ling Yang1†
Xiaoli Huang
Fei Hua
Xiaoyu Yang- 1Department of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou, China
- 2Department of Endocrinology, The Third Affiliated Hospital of Soochow University, Changzhou, China
A Corrigendum on
Reconstruction and Analysis of the lncRNA-miRNA-mRNA Network Based on Competitive Endogenous RNA Reveal Functional lncRNAs in Dilated Cardiomyopathy
by Tao, L., Yang, L., Huang, X., Hua, F., and Yang, X. (2019). Front. Genet. 10: 1149. doi: 10.3389/fgene.2019.01149
In the original article, an incorrect representative image of immunofluorescent staining for cardiac fibroblasts was contained in Figure 6G as published. The immunofluorescent staining of EdU/α-SMA in Figure 6G (nc agomir group) was duplicated as Figure 6I (nc antagomir group), which was mistakenly presented. The correct representative images for Figure 6G appear below.
FIGURE 6
FIGURE 6. Functional study of miR-144-3p in vitro. (A). qRT-PCR analysis of miRNA between cardiomyocytes and fibroblasts (n = 6). (B,C). qRT-PCR analysis of the transfection efficacy of miR-144-3p with agomir/antagomir compared to controls (n = 6). (C–E). Overexpression or downregulation of miR-144-3p did not perform effects on cardiomyocyte cell size and pathological hypertrophic markers (ANP and BNP), as evidence by α-actin/DAPI staining (n = 4) and qRT-PCR analysis (n = 6). (F). Decreased expression of miR-144-3p in cardiac fibrosis model induced by TGFβ (n = 6). (G,H). Forced expression of miR-144-3p attenuated TGFβ-induced cardiac fibroblast proliferation and trans-differentiation, as evidenced by EdU/α-SMA staining (n = 4) and qRT-PCR analysis of α-SMA, Col1a1 and Col3a1 (n = 6) (I,J). inhibition of miR-144-3p deteriorated TGFb-induced cardiac fibroblasts proliferation and trans-differentiation as evidenced by EdU/α-SMA staining (n = 4) and qRT-PCR analysis (n = 6). Scale bar: 50um. *, p < 0.05; **, p < 0.01; ***, p < 0.001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: long non-coding RNA, microRNA, competitive endogenous RNA, lncRNA-miRNA-, dilated cardiaomypothy
Citation: Tao L, Yang L, Huang X, Hua F and Yang X (2022) Corrigendum: Reconstruction and Analysis of the lncRNA-miRNA-mRNA Network Based on Competitive Endogenous RNA Reveal Functional lncRNAs in Dilated Cardiomyopathy. Front. Genet. 13:896402. doi: 10.3389/fgene.2022.896402
Received: 16 March 2022; Accepted: 16 March 2022;
Published: 25 April 2022.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2022 Tao, Yang, Huang, Hua and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Fei Hua, aHVhZmVpMTk3MEBzdWRhLmNu; Xiaoyu Yang, anNjenl4eUAxNjMuY29t
†These authors have contributed equally to this work