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CASE REPORT article

Front. Endocrinol.
Sec. Bone Research
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1447652
This article is part of the Research Topic Phosphate handling: from cells to human View all 4 articles

Non-parathyroid hypercalcemia in a patient with new-onset hyperthyroidism and silicone-induced granulomas: case report

Provisionally accepted
Laura Montefusco Laura Montefusco 1*Giada Rossi Giada Rossi 2Iulia Petria Iulia Petria 2Ida Pastore Ida Pastore 1,2Paolo Fiorina Paolo Fiorina 1,3,4
  • 1 ASST Fatebenefratelli Sacco, Milan, Italy
  • 2 Department of Biomedical and Clinical Sciences, Faculty of Medicine and Surgery, University of Milan, Milan, Lombardy, Italy
  • 3 Division of Nephrology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States
  • 4 Pediatric Research Center Romeo and Enrica Invernizzi Hospital, Milan, Lombardy, Italy

The final, formatted version of the article will be published soon.

    Background: Hypercalcemia is a frequent occurrence in hospitalized patients. It can vary in presentation and severity, and appropriate treatment requires targeting of the underlying condition.Rarer causes of hypercalcemia, such as hyperthyroidism and granulomatous diseases, need to be addressed after excluding the more prevalent etiologies, namely primary hyperparathyroidism and malignancies. We report a case of moderate hypercalcemia in a patient with HIV-positivity with newonset autoimmune hyperthyroidism as well as concomitant chronic granulomas due to silicone injections.

    Keywords: Hypercalcemia, Hyperthyroidism, Granulomatosis, Tumor-induced hypercalcemia, case report

    Received: 11 Jun 2024; Accepted: 23 Dec 2024.

    Copyright: © 2024 Montefusco, Rossi, Petria, Pastore and Fiorina. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Laura Montefusco, ASST Fatebenefratelli Sacco, Milan, Italy

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.