A Novel Resveratrol Analog Upregulates SIRT1 Expression and Ameliorates Neointima Formation
- 1Wuxi School of Medicine and School of Food Science and Technology, Jiangnan University, Wuxi, China
- 2State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, China
- 3School of Pharmacy, Fudan University, Shanghai, China
A corrigendum on
A novel resveratrol analog upregulates SIRT1 expression and ameliorates neointima formation
by Yuan, B., Liu, H., Dong, X., Pan, X., Sun, X., Sun, J., and Pan, L.-L. (2021). Front. Cardiovasc. Med. 8:756098. doi: 10.3389/fcvm.2021.756098
In the published article, there was an error in Figures 1, 2 as published. Due to our mistake in combining images, two graphs in Figures 1B, 2D were misused. The corrected Figures 1, 2 appear below.
![www.frontiersin.org](https://www.frontiersin.org/files/Articles/986353/fcvm-09-986353-HTML/image_m/fcvm-09-986353-g001.jpg)
Figure 1. (R)-TML104 mitigates injury-induced neointima formation in vivo. (A) Hematoxylin and Eosin (H&E) staining of sections at 28 days after injury (Scale bar: 50 μm). (B) Immunofluorescence staining of α-SMA, PCNA, and cyclin D1 on sections of carotid arteries from mice. Scale bar: 50 μm, Data shown are means ± S.D (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001.
![www.frontiersin.org](https://www.frontiersin.org/files/Articles/986353/fcvm-09-986353-HTML/image_m/fcvm-09-986353-g002.jpg)
Figure 2. (R)-TML104 inhibits PDGF-BB-induced VSMC phenotypic transformation in vitro. (A) VSMC were pretreated with (R)-TML104 for 4 h and then stimulated with PDGF-BB (20 ng/mL) for 24 h. The protein levels of α-SMA, PCNA, and cyclin D1 were determined by western blotting. (B) The protein levels of α-SMA, PCNA, and cyclin D1 were determined by western blotting. (C) DNA synthesis in VSMC was determined with an EdU incorporation assay. Blue fluorescence (Hoechst 33342) showed cell nuclei and green fluorescence (EdU) stands for cells with DNA synthesis. (D) Transwell assay was performed to determine the migration of VSMC. Scale bar: 50 μm, Data shown are means ± S.D (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: (R)-TML104, neointima formation, nicotinamide adenine dinucleotide phosphate oxidase 4, nuclear factor-κB, vascular smooth muscle cells, reactive oxygen species, SIRT1
Citation: Yuan B, Liu H, Dong X, Pan X, Sun X, Sun J and Pan L-L (2022) Corrigendum: A novel resveratrol analog upregulates SIRT1 expression and ameliorates neointima formation. Front. Cardiovasc. Med. 9:986353. doi: 10.3389/fcvm.2022.986353
Received: 05 July 2022; Accepted: 18 July 2022;
Published: 05 August 2022.
Edited and reviewed by: Bo Liu, University of Wisconsin-Madison, United States
Copyright © 2022 Yuan, Liu, Dong, Pan, Sun, Sun and Pan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Li-Long Pan, llpan@jiangnan.edu.cn; Jia Sun, jiasun@jiangnan.edu.cn; Xun Sun, sunxunf@shmu.edu.cn
†These authors have contributed equally to this work and share first authorship