This article is a correction to:
Corrigendum: Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion
Song-Song Zou1,2,3,4Qing-Cui Zou1,2,3,4Wen-Jing Xiong1,2,3,4Ning-Yi Cui1,2,3,4Ke Wang1,2,3,4Hao-Xuan Liu1,2,3,4Wen-Juan Lou1,2,3,4Doaa Higazy1,2,3,4Ya-Ge Zhang1,2,3,4
Min Cui1,2,3,4*- 1State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- 2Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China
- 3Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture of the People’s Republic of China, Wuhan, China
- 4International Research Center for Animal Disease, Ministry of Science and Technology of the People’s Republic of China, Wuhan, China
A Corrigendum on
Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion
by Zou S-S, Zou Q-C, Xiong W-J, Cui N-Y, Wang K, Liu H-X, Lou W-J, Higazy D, Zhang Y-G and Cui M (2021). 11:701820. doi: 10.3389/fcimb.2021.701820
In the original article, there was a mistake in Figures 5D–E as published. Images repeated of Figures 5D–E. The corrected Figure 5 appears below.
FIGURE 5
Figure 5 Virus-carrying splenocyte transmigration in vitro. (A–C) JEV-infected bEnd.3 cell monolayers were cocultured with EGFP-JEV-infected splenocytes (5 × 105) for 24 h, and the transmigrated cells (lower chamber) were collected and measured by flow cytometry. An enhanced sensitivity measure at 488 nm was performed for the detection of intracellular EGFP-JEV in CD19+ B cells, CD3+ T cells, and Ly6C+ CD11b+ monocytes by flow cytometry. EGFP-JEV free cells were the nonspecific control. (D, E) The statistical analysis of EGFP-positive cells in the transmigrated cells in the lower chamber reported in (A–C). The experiments were repeated at least three times. The data are expressed as the means ± SEM. p > 0.05 (ns, no significant difference), *p < 0.05 and **p < 0.01.
In the original article, there was an error in the description of Figure 5D.
A correction has been made to Results, Extracellular HMGB1 Facilitated Transendothelial Migration of JEV-Infected Monocytes, **paragraph 3:
To discover which cells act as virus carriers, JEV with an EGFP tag (EGFP-JEV) was applied to visualize cell transmigration. There was an increased percentage of EGFP-positive Ly6C+CD11b+ monocytes, CD3+ T cells, and CD19+ B cells that transmigrated, compared with the control cells (Figures 5A–C). Furthermore, there were significantly more transmigrated JEV-positive (EGFP+Ly6C+CD11b+) monocytes than transmigrated JEV-positive T cells (EGFP+CD3+) or B cells (EGFP+CD19+) (Figures 5D, E).
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publisher’s Note
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Keywords: transmigration, adhesion, monocyte, HMGB1, Japanese encephalitis virus (JEV), neuroinvasion
Citation: Zou S-S, Zou Q-C, Xiong W-J, Cui N-Y, Wang K, Liu H-X, Lou W-J, Higazy D, Zhang Y-G and Cui M (2022) Corrigendum: brain microvascular endothelial cell-derived HMGB1 facilitates monocyte adhesion and transmigration to promote JEV neuroinvasion. Front. Cell. Infect. Microbiol. 12:964880. doi: 10.3389/fcimb.2022.964880
Received: 09 June 2022; Accepted: 14 July 2022;
Published: 29 July 2022.
Edited and Reviewed by:
Abrar Hussain, Balochistan University of Information Technology, Engineering and Management Sciences, PakistanCopyright © 2022 Zou, Zou, Xiong, Cui, Wang, Liu, Lou, Higazy, Zhang and Cui. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Min Cui, cuimin@mail.hzau.edu.cn