This article is a correction to:
Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
Angela Maria Giada Giovenale1,2†Giorgia Ruotolo1,2†Amata Amy Soriano1Elisa Maria Turco1Giovannina Rotundo1Alessia Casamassa1Angela D’Anzi1Angelo Luigi Vescovi1,2*
Jessica Rosati1*- 1Cellular Reprogramming Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San GiovanniRotondo, Italy
- 2Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
A Corrigendum on
Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
by Giovenale AMG, Ruotolo G, Soriano AA, Turco EM, Rotundo G, Casamassa A, D’Anzi A, Vescovi AL and Rosati J (2023). Front. Cell Dev. Biol. 10:1107881. doi: 10.3389/fcell.2022.1107881
In the published article, there is an error in Figure 3 and Figure 4 as published. The two figures are inverted, while the captions are correct. The corrected Figure 3 and Figure 4 and its caption appear below.
FIGURE 3
FIGURE 3. Chromosome 15q13.3 and hiPSCs derived from individuals with CNV. Graphic representation of chromosomal region 15q13.3 showing BreakPoint regions BP3, BP4 and BP5 and the extensions the microdeletions and microduplications present in the hiPSCs in the published studies.
FIGURE 4
FIGURE 4. An insight into molecular effects of CNV 15q13.3. Cells carrying CNV duplications show decreased calcium flux associated with the α7 receptor, downregulation of JAK2-PI3K pathway, decreased assembly and trafficking of nAchRs, and ER stress. Cells carrying CNV deletions exhibit decreased α7nAchRs calcium flux and downregulation of JAK2-PI3K pathway.
In the published article, there is an error in Table 1 as published. The table is not paginated correctly. Table 1 and its caption appear below.
TABLE 1
TABLE 1. Summary of the studies based on the hiPSCs model for studying 15q13.3 CNV.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: neurodevelopmental disorders, neuropsychiatric disorders, 15q11-13, CHRNA7, nicotinic acetylcholine receptor, copy number variation, CNV
Citation: Giovenale AMG, Ruotolo G, Soriano AA, Turco EM, Rotundo G, Casamassa A, D’Anzi A, Vescovi AL and Rosati J (2023) Corrigendum: Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview. Front. Cell Dev. Biol. 11:1141334. doi: 10.3389/fcell.2023.1141334
Received: 10 January 2023; Accepted: 16 January 2023;
Published: 01 February 2023.
Edited and reviewed by:
Mirella Dottori, University of Wollongong, AustraliaCopyright © 2023 Giovenale, Ruotolo, Soriano, Turco, Rotundo, Casamassa, D’Anzi, Vescovi and Rosati. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Jessica Rosati, ai5yb3NhdGlAY3NzLW1lbmRlbC5pdA==; Angelo Luigi Vescovi, YW5nZWxvLnZlc2NvdmlAdW5pbWliLml0
†These authors have contributed equally to this work