This article is a correction to:
GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT
En Xu1
Xuefeng Xia1*
Chaoyu Jiang1Zijian Li2Zhi Yang2
Chang Zheng3Xingzhou Wang1Shangce Du1Ji Miao1Feng Wang1Yizhou Wang1Xiaofeng Lu2*
Wenxian Guan1*- 1Department of General Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China
- 2Department of General Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
- 3Department of Gastroenterology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China
A Corrigendum on
GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT
by Xu, E., Xia, X., Jiang, C., Li, Z., Yang, Z., Zheng, C., Wang, X., Du, S., Miao, J., Wang, F., Wang, Y., Lu, X., and Guan, W. (2020). Front Cell Dev Biol. 8 591239. doi: 10.3389/fcell.2020.591239
Error in Figure
In the original article, there was a mistake in Figures 3, 4 as published. In Figures 3D, 4C, we put the wrong picture due to carelessness. The corrected Figures 3, 4 appear below.
FIGURE 3
FIGURE 3. GPER1 knockdown impairs the proliferation of AGS and MGC-803 cells. (A) CCK-8 and (B) Edu assays were used to evaluate the proliferation of AGS and MGC-803 cells after transfection with siGPER1 for 48 h; (C) Flow cytometry and (D) CDK4 and cyclin D1 protein levels were used to analyze the cell cycle of AGS and MGC-803 cells after transfection with siGPER1 for 48 h. Control: cells without transfection; GPER1, cells transfected with GPER1 siRNA; 740Y-P, cells treated with 740Y-P; GPER1 + 740Y-P, cells transfected GPER1 siRNA and then treated with 740Y-P. Results were shown as mean ± SD of three independent experiments, each experiment was performed in triplicate. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
FIGURE 4
FIGURE 4. GPER1 knockdown impairs the migration and invasion of AGS and MGC-803 cells. (A) Cell mobility was detected by wound healing assay; (B) cell migration and (C) invasion were detected by transwell assays; (D). Western blot analysis of matrix metalloproteinase 9 (MMP9) and MMP2 protein expression. GAPDH was used as a loading control. Control, cells without transfection; GPER1, cells transfected with GPER1 siRNA; 740Y-P, cells treated with 740Y-P; GPER1 + 740Y-P, cells transfected GPER1 siRNA and then treated with 740Y-P. Results were shown as mean ± SD of three independent experiments, each experiment was performed in triplicate. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: GPER1, EMT, migration, invasion, gastric cancer
Citation: Xu E, Xia X, Jiang C, Li Z, Yang Z, Zheng C, Wang X, Du S, Miao J, Wang F, Wang Y, Lu X and Guan W (2022) Corrigendum: GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT. Front. Cell Dev. Biol. 10:841792. doi: 10.3389/fcell.2022.841792
Received: 22 December 2021; Accepted: 24 January 2022;
Published: 23 February 2022.
Edited by:
Xing Huang, Zhejiang University, ChinaCopyright © 2022 Xu, Xia, Jiang, Li, Yang, Zheng, Wang, Du, Miao, Wang, Wang, Lu and Guan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xuefeng Xia, danielxuefeng@hotmail.com; Xiaofeng Lu, lxf_njglyy@sina.com; Wenxian Guan, 15850502391@163.com