Hypoxia Response Element-Directed Expression of aFGF in Neural Stem Cells Promotes the Recovery of Spinal Cord Injury and Attenuates SCI-Induced Apoptosis
- 1Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
- 2Molecular Pharmacology Research Center, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China
- 3Department of Pain Medicine, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
by Ying, Y., Zhang, Y., Tu, Y., Chen, M., Huang, Z., Ying, W., Wu, Q., Ye, J., Xiang, Z., Wang, X., Wang, Z., and Zhu, S. (2021). Front. Cell Dev. Biol. 9:693694. doi: 10.3389/fcell.2021.693694
In the published article, there was an error in Figure 5 as published. There were similar blocks of EIF-2α and CHOP staining in the AAV-5HRE-NSCs group in Figure 5. The corrected Figure 5 and its caption appear below.
FIGURE 5. The regulation signals are significant for the neuroprotective effect of AAV–5HRE–aFGF–NSCs. (A) Immunohistochemistry for caspase 12, caspase 3, EIF–2a–CHOP, and GRP78 in the Sham, SCI, AAV–5HRE–NSCs, and AAV–5HRE–aFGF–NSCs group. Magnification: 20×; Scale: 100 μm. (B–F) Analysis of immunohistochemistry positive cells. **p < 0.01. #p < 0.05. ##p < 0.01. Data are represented as mean ± SD (n = 6).
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: spinal cord injury, acidic fibroblast growth factor, adeno-associated virus, neural stem cell, endoplasmic reticulum stress, apoptosis
Citation: Ying Y, Zhang Y, Tu Y, Chen M, Huang Z, Ying W, Wu Q, Ye J, Xiang Z, Wang X, Wang Z and Zhu S (2022) Corrigendum: Hypoxia response element-directed expression of aFGF in neural stem cells promotes the recovery of spinal cord injury and attenuates SCI-induced apoptosis. Front. Cell Dev. Biol. 10:1011414. doi: 10.3389/fcell.2022.1011414
Received: 04 August 2022; Accepted: 24 August 2022;
Published: 13 September 2022.
Edited and reviewed by:
Yidong Wang, Xian Jiaotong University, ChinaCopyright © 2022 Ying, Zhang, Tu, Chen, Huang, Ying, Wu, Ye, Xiang, Wang, Wang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xiangyang Wang, xiangyangwang@wmu.edu.cn Zhouguang Wang, wzhouguang@gmail.com Sipin Zhu, sipinzhu@163.com
†These authors have contributed equally to this work