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CORRECTION article

Front. Cell Dev. Biol., 13 September 2022
Sec. Stem Cell Research
This article is part of the Research Topic Stem/Progenitor Cells and Their Microenvironment in Brain Development and Tumor Biology View all 6 articles

Corrigendum: Hypoxia response element-directed expression of aFGF in neural stem cells promotes the recovery of spinal cord injury and attenuates SCI-induced apoptosis

  • 1Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China
  • 2Molecular Pharmacology Research Center, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, China
  • 3Department of Pain Medicine, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China

A Corrigendum on
Hypoxia response element-directed expression of aFGF in neural stem cells promotes the recovery of spinal cord injury and attenuates SCI-induced apoptosis

by Ying, Y., Zhang, Y., Tu, Y., Chen, M., Huang, Z., Ying, W., Wu, Q., Ye, J., Xiang, Z., Wang, X., Wang, Z., and Zhu, S. (2021). Front. Cell Dev. Biol. 9:693694. doi: 10.3389/fcell.2021.693694

In the published article, there was an error in Figure 5 as published. There were similar blocks of EIF-2α and CHOP staining in the AAV-5HRE-NSCs group in Figure 5. The corrected Figure 5 and its caption appear below.

FIGURE 5
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FIGURE 5. The regulation signals are significant for the neuroprotective effect of AAV–5HRE–aFGF–NSCs. (A) Immunohistochemistry for caspase 12, caspase 3, EIF–2a–CHOP, and GRP78 in the Sham, SCI, AAV–5HRE–NSCs, and AAV–5HRE–aFGF–NSCs group. Magnification: 20×; Scale: 100 μm. (B–F) Analysis of immunohistochemistry positive cells. **p < 0.01. #p < 0.05. ##p < 0.01. Data are represented as mean ± SD (n = 6).

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: spinal cord injury, acidic fibroblast growth factor, adeno-associated virus, neural stem cell, endoplasmic reticulum stress, apoptosis

Citation: Ying Y, Zhang Y, Tu Y, Chen M, Huang Z, Ying W, Wu Q, Ye J, Xiang Z, Wang X, Wang Z and Zhu S (2022) Corrigendum: Hypoxia response element-directed expression of aFGF in neural stem cells promotes the recovery of spinal cord injury and attenuates SCI-induced apoptosis. Front. Cell Dev. Biol. 10:1011414. doi: 10.3389/fcell.2022.1011414

Received: 04 August 2022; Accepted: 24 August 2022;
Published: 13 September 2022.

Edited and reviewed by:

Yidong Wang, Xian Jiaotong University, China

Copyright © 2022 Ying, Zhang, Tu, Chen, Huang, Ying, Wu, Ye, Xiang, Wang, Wang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Xiangyang Wang, xiangyangwang@wmu.edu.cn Zhouguang Wang, wzhouguang@gmail.com Sipin Zhu, sipinzhu@163.com

These authors have contributed equally to this work

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.