Skip to main content

ORIGINAL RESEARCH article

Front. Bioeng. Biotechnol., 25 November 2024
Sec. Biomechanics
This article is part of the Research Topic Assessment and Monitoring of Human Movement View all 34 articles

Biomechanical analysis of limits of stability using computerized posturography: correlations with functional mobility in elderly individuals with hip osteoarthritis – a cross-sectional study

  • Biomechanics and Research Lab, Program of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia

Background: Hip osteoarthritis (OA) is a degenerative joint disease that predominantly affects the elderly, causing significant morbidity due to joint pain, stiffness, and loss of function. This study aimed to assess the limits of stability (LOS) using computerized posturography and evaluate the correlations with functional mobility in elderly individuals with hip OA.

Methods: This cross-sectional study included elderly individuals aged 65 years and above with a clinical diagnosis of hip OA and age-matched asymptomatic controls. The LOS was measured using a computerized dynamic posturography system, which quantified the maximum distance and angle participants could shift their center of gravity without losing balance. Functional mobility was assessed using the Timed Up and Go (TUG) test, which measures the time taken for participants to stand up, walk 3 m, turn around, walk back, and sit down.

Results: The study included 86 elderly individuals with hip OA and 86 age-matched asymptomatic controls. LOS assessments showed that individuals with hip OA had significantly lower stability scores across all directions compared to controls (p < 0.001). TUG test times were significantly slower for the OA group (10.50 ± 2.20 s) compared to controls (8.70 ± 2.00 s, p < 0.001). Positive correlations were found between LOS and functional mobility (r = 0.50, p = 0.009). Moderation analysis revealed that age and duration of OA significantly influenced the relationship between stability and mobility.

Conclusion: Hip OA significantly impacts stability and functional mobility in elderly individuals. Enhanced stability is associated with improved mobility, and demographic and clinical variables such as age and duration of OA play crucial roles in these relationships. These findings underscore the importance of targeted therapeutic interventions to improve stability and mobility in this population.

1 Introduction

Hip osteoarthritis (OA) is a degenerative joint disease that predominantly affects the elderly, leading to significant morbidity due to joint pain, stiffness, and loss of function (Abramoff and Caldera, 2020). Characterized by the gradual deterioration of cartilage and changes in the periarticular bone, hip OA is a major cause of impaired mobility and reduced quality of life among older adults (Murphy et al., 2016). It remains a public health challenge due to its increasing prevalence in the aging population and the substantial personal and socioeconomic burdens it imposes (Egerton et al., 2018). Although the pathogenesis of hip OA involves biomechanical and inflammatory processes that alter joint structure and function, the specific contributions of these changes to the functional impairments observed in individuals remain to be fully elucidated (Litwic et al., 2013).

The concept of “limits of stability” (LOS) is critical in understanding how individuals maintain balance when their center of gravity approaches the boundaries of their base of support (Nolff et al., 2024). LOS represents the maximum angle or distance one can tilt or move without losing balance, stepping, or falling (Cella et al., 2020). In patients with hip OA, LOS may be significantly compromised due to joint instability, pain, muscular weakness, and compensatory gait adaptations (Boekesteijn et al., 2021). These biomechanical constraints not only limit movement but also contribute to an increased risk of falls (Sturnieks, 2021). Thus, evaluating LOS in the context of hip OA can provide insights into the extent of mobility limitations and the effectiveness of various therapeutic interventions aimed at restoring balance and preventing falls (Grabiner and Kaufman, 2021).

Functional mobility, defined as the ability to move independently to carry out activities of daily living, is a key determinant of autonomy and quality of life in the elderly (Tornero-Quiñones et al., 2020). In the context of hip OA, functional mobility is often compromised, with affected individuals experiencing difficulties in walking, climbing stairs, and performing other activities that require joint movement and stability (Do and Yim, 2020). The deterioration in functional mobility is primarily due to pain, muscle weakness, and joint stiffness, which directly affect the stability and biomechanical efficiency of the hip (Boekesteijn et al., 2021). Consequently, there is a profound need to explore the relationships between LOS, joint stability, and functional mobility to develop targeted strategies that can enhance the quality for those afflicted.

Despite extensive research on hip OA, there remains a significant gap in understanding how demographic and clinical variables modulate the relationship between stability and functional mobility in this population (Laitner et al., 2021). Previous studies have primarily focused on the impact of OA on overall physical function with less emphasis on specific biomechanical measurements such as LOS and their correlation with everyday functional tasks (Wilson and Kobsar, 2021). Moreover, the influence of factors such as age, disease duration, and body mass index on these relationships has not been adequately addressed (Batushansky et al., 2022). This lack of detailed knowledge hampers the development of customized treatment and rehabilitation protocols that address the specific needs of different patient subgroups (Brembo, 2020). Therefore, a comprehensive study integrating biomechanical, clinical, and demographic variables is essential to elucidate these complex interactions and guide clinical practice.

This study aims to fill these research gaps by 1) comparing the limits of stability and functional mobility in elderly individuals with hip osteoarthritis versus age-matched asymptomatic controls; 2) evaluating the association between stability limits and functional mobility within the hip OA group; and 3) conducting a moderation analysis to determine how age, gender, body mass index, and duration of osteoarthritis diagnosis influence these relationships. The hypotheses are that stability limits will be significantly lower, functional mobility will be more impaired in individuals with hip OA compared to controls, and the severity of these impairments will be moderated by demographic and clinical variables. These objectives will provide a comprehensive understanding of the biomechanical deficits in hip OA and support the development of targeted interventions to improve stability and mobility in this vulnerable population.

2 Materials and methods

2.1 Study design, settings, and duration

This descriptive cross-sectional study took place from June 2022 to May 2023 in the Physical Therapy Department of King Khalid University Hospital, a tertiary care facility located in Abha, Saudi Arabia, which focuses on geriatric and orthopedic care. The participants were enlisted from the outpatient orthopedic clinic and the geriatric department within the hospital. The research protocol was reviewed and approved by the King Khalid University Institutional Review Board (approval number REC# 456–872) and conformed to the ethical guidelines outlined in the Declaration of Helsinki. All participants provided written informed consent before inclusion in the study.

2.2 Participants

The study involved elderly individuals aged 65 and above, both with and without hip osteoarthritis, who were recruited from outpatient orthopedic clinics in Abha, Saudi Arabia. The inclusion criteria for the osteoarthritis group were a clinical diagnosis of hip osteoarthritis based on the American College of Rheumatology criteria, the ability to walk independently, and willingness to participate in the study (van Doormaal et al., 2020). Age-matched asymptomatic controls were selected based on the absence of hip pain, osteoarthritis, or other musculoskeletal disorders. Participants who were able to understand and follow study instructions and who provided written informed consent were also included. Exclusion criteria for both groups were comprehensive to ensure the validity of the study. Individuals were excluded if they had other musculoskeletal disorders that could affect balance and mobility, such as severe knee osteoarthritis or lower limb fractures. Neurological conditions which could impair balance, were also grounds for exclusion. Cognitive impairments, determined by a score of less than 24 on the Mini-Mental State Examination (MMSE), were another exclusion criterion, as such impairments could interfere with the ability to understand and perform the study tasks. Participants who had undergone hip replacement surgery or other major lower limb surgeries within the past 6 months were excluded to avoid confounding factors related to recent surgical recovery. Additionally, individuals with severe visual or auditory impairments that could affect their ability to follow instructions or perform the tasks were not included. Lastly, any participant with an unstable medical condition or comorbidity that could pose a risk during the study assessments, such as uncontrolled hypertension or severe cardiovascular disease, was excluded.

2.3 Limits of stability assessment

The LOS were assessed using computerized dynamic posturography, which incorporates a stabilometric posture platform, a touch screen, a 3D camera, and dedicated software (Fonseca et al., 2021). This system measures the maximum distance and angle at which participants can shift their center of gravity without losing balance, stepping, or falling (De Jong et al., 2020). The LOS assessments were performed in a calm, well-ventilated setting. Participants stood on the stabilometric force platform with their feet together in a standardized position, facing a screen that displayed targets (Figure 1). These targets appeared randomly in eight directions: forward, backward, left, right, and intermediate diagonal directions (left-forward, right-forward, left-backward, right-backward) (Palm et al., 2014). Participants were instructed to shift their center of mass toward the targets without moving their feet. The posturography system recorded the amount of sway required to reach each target, providing a score based on the precision of movement along the shortest vertical or horizontal path. A score of 100 indicated perfect stability in a given direction, while lower scores reflected greater sway and reduced stability. This methodology ensured that LOS data were collected with high consistency and accuracy, yielding reliable measurements of the participants’ balance and stability capabilities.

Figure 1
www.frontiersin.org

Figure 1. Evaluation of Stability Boundaries in eight directions, illustrated with panel showing the initial starting position and panel displaying the participant reaching a predetermined target, as seen in computerized posturography.

2.4 Functional mobility assessment

Functional mobility was assessed using the TUG test, which is a widely recognized and reliable measure of functional mobility and fall risk (Bergquist et al., 2020). During the TUG test, participants are timed as they rise from a seated position in a standard armchair, walk 3 m, turn around, walk back to the chair, and sit down again. This evaluation provides a quick and practical measure of the basic mobility skills necessary for daily activities. The test was conducted in a well-lit, unobstructed corridor within the hospital to ensure both safety and accuracy. Participants received clear instructions to perform the task at their usual walking pace, reflecting their typical level of mobility. The time required to complete the TUG test was recorded in seconds using a calibrated stopwatch. Performance on the TUG test serves as a key indicator of functional mobility, with shorter times indicating better mobility (Rose et al., 2002).

2.5 Pain and Disability Scores

Pain levels were measured using the Visual Analog Scale (VAS), where participants rated their pain on a scale from 0 (no pain) to 10 (worst pain imaginable). Functional disability was evaluated using the Harris Hip Score, a standardized questionnaire that assesses pain, function, absence of deformity, and range of motion.

2.6 Sample size estimation

The sample size for our cross-sectional study was determined using G*Power statistical software, version 3.1.9.4. We targeted an effect size of 0.4 to detect moderate effects of hip osteoarthritis on stability and mobility (Alkhamis et al., 2024). For the limits of stability (LOS), we assumed a mean of 78.00 (SD = 9.00) for the control group and 68.00 (SD = 8.00) for the OA group. For the Timed Up and Go (TUG) test, the assumed means were 8.70 s (SD = 2.00) for the control group and 10.50 s (SD = 2.20) for the OA group. Cohen’s d was computed as the difference in means divided by the pooled standard deviation. For LOS, Cohen’s d was calculated as [(78.00–68.00)/8.53] ≈ 0.50, and for TUG as [(10.50–8.70)/2.10] ≈ 0.85. Calculations aimed for a power of 0.80 and an alpha level of 0.05, indicating that 86 participants per group were required to conduct reliable independent samples t-tests, correlation analyses, and moderation analyses.

2.7 Data analysis section

Data processing and analysis were conducted using the Statistical Package for the Social Sciences (SPSS), version 21. Preliminary checks for normality and outliers ensured that the assumptions for parametric statistical testing were met, as indicated by the Shapiro-Wilk tests and acceptable levels of skewness and kurtosis, confirming that data distributions were approximately normal. For Objective 1, we employed independent samples t-tests to compare the LOS and functional mobility between elderly individuals with hip OA and age-matched asymptomatic individuals, with Cohen’s d calculated to assess effect sizes. Objective 2 involved analyzing the relationship between stability limits and functional mobility using Pearson correlation coefficients to explore the strength and direction of their association in the hip OA group. For Objective 3, moderation analysis with multiple regression models tested how demographic and clinical variables such as age, gender, body mass index (BMI), and duration of OA diagnosis might moderate this relationship (Jie et al., 2015). Interaction terms were created and simple slopes analysis was performed for significant interactions, adjusting for multiple comparisons to ensure precise interpretation. Assumptions of multicollinearity, independence of residuals, homoscedasticity, and linearity were thoroughly checked through diagnostic plots and tests, including VIF and Durbin-Watson, to validate the regression models (Srinivasan et al., 2017). All statistical tests were two-tailed with a significance level set at p < 0.05, providing a robust and reliable framework for evaluating the effects of stability and mobility in our study population.

3 Results

The demographic and clinical characteristics of the study participants reveal significant differences in Body Mass Index (BMI), Pain, VAS, and Disability Scores between elderly individuals with hip osteoarthritis and asymptomatic controls, while age and gender distribution show no significant differences (Table 1). Specifically, participants with hip osteoarthritis had a higher average BMI (29.13 ± 4.25) compared to controls (27.56 ± 3.89), with a statistically significant difference (p = 0.013). The Hip Osteoarthritis group had an average duration of osteoarthritis diagnosis of 5.25 ± 2.67 years, a mean pain score of 6.54 ± 1.28 on the Visual Analog Scale (VAS), and a mean disability score of 62.35 ± 8.14 based on the Harris Hip Score.

Table 1
www.frontiersin.org

Table 1. Demographic and clinical characteristics of study participants.

The analysis presented in Table 2 underscores the marked differences in LOS and functional mobility between elderly individuals with hip osteoarthritis and age-matched asymptomatic controls. Notably, the group with hip osteoarthritis demonstrated significantly lower stability percentages across all directional measures, with the forward direction showing the greatest disparity: 41.20 ± 4.50 for osteoarthritis patients compared to 78.00 ± 9.00 for controls, and a p-value of less than 0.001. Similar significant differences were observed in other directions, including the right-forward direction (68.00 ± 8.00 vs. 88.00 ± 11.00), right (72.00 ± 11.00 vs. 92.00 ± 12.00), and left-forward (88.00 ± 11.00 vs. 97.00 ± 14.00), all with p-values below 0.001. Cohen’s d values indicate moderate to large effect sizes, particularly notable in the right-forward direction (0.50) and total objective measures (0.49). Additionally, functional mobility as assessed by the TUG score showed osteoarthritis patients had significantly slower times (10.50 ± 2.20) compared to controls (8.70 ± 2.00), reflecting greater mobility impairment, again with a highly significant p-value (<0.001) and a large effect size (Cohen’s d = 9.85).

Table 2
www.frontiersin.org

Table 2. Limits of stability and functional mobility in elderly individuals with hip osteoarthritis vs. age-matched asymptomatic controls.

The analysis detailed in Table 3 demonstrates a significant correlation between stability limits and functional mobility in elderly individuals with hip osteoarthritis (Figure 2). Positive correlations are evident across various directions, indicating that as stability increases, so does functional mobility. The strongest positive correlation is observed in the total objective measure (r = 0.50, p = 0.009), suggesting that overall stability is a strong predictor of better functional mobility outcomes. Notably, the TUG Score, which inversely measures mobility (lower scores indicate better mobility), shows a significant negative correlation (r = −0.45, p = 0.022) with stability limits, reinforcing the relationship between increased stability and enhanced mobility capabilities. Each directional measurement, from forward to left-forward, displays moderate positive correlations, with p-values ranging from 0.018 to 0.049, underscoring the consistent impact of stability on mobility across different axes of movement.

Table 3
www.frontiersin.org

Table 3. Association between stability limits and functional mobility in elderly individuals with hip osteoarthritis.

Figure 2
www.frontiersin.org

Figure 2. Association between stability limits and functional mobility in elderly individuals with hip osteoarthritis.

The moderation analysis in Table 4 reveals how demographic and clinical variables influence stability and mobility in elderly individuals with hip osteoarthritis (Figure 3). Age and duration of osteoarthritis diagnosis are significant moderators in this relationship. Specifically, older age shows a positive interaction effect on mobility and stability (β = 0.12, p = 0.038), indicating that as age increases, the positive impact on the association between stability and mobility also increases. Similarly, a longer duration of osteoarthritis diagnosis significantly strengthens the relationship (β = 0.14, p = 0.022), suggesting that those who have lived longer with the diagnosis experience greater effects on their mobility and stability. In contrast, BMI shows a moderate positive influence (β = 0.09, p = 0.046), while gender does not significantly moderate the relationship (β = −0.07, p = 0.110), indicating no statistically significant differences between males and females. Although the hip osteoarthritis group had a significantly higher BMI compared to the control group, moderation analysis demonstrated that BMI had a moderate influence on the relationship between stability and functional mobility (β = 0.09, p = 0.046). However, the primary driver of balance and mobility impairments was the presence of osteoarthritis, indicating that while BMI contributed to the outcomes, it did not solely account for the observed differences.

Table 4
www.frontiersin.org

Table 4. Moderation analysis of demographic and clinical variables on stability and mobility in elderly individuals with hip osteoarthritis.

Figure 3
www.frontiersin.org

Figure 3. Moderation analysis of demographic and clinical variables affecting stability and mobility in elderly individuals with hip osteoarthritis.

4 Discussion

This study investigated the impact of hip osteoarthritis on stability and functional mobility among elderly patients. Significant differences were identified in both stability and mobility between patients with osteoarthritis and age-matched asymptomatic controls, with those suffering from osteoarthritis showing reduced stability and impaired mobility. Analyses demonstrated a positive correlation between stability limits and functional mobility within the osteoarthritis group, suggesting that enhanced stability is associated with improved mobility. Furthermore, moderation analysis indicated that age and the duration of osteoarthritis diagnosis significantly influence the relationship between stability and mobility, where increased age and longer disease duration exacerbate mobility limitations. These results underscore the need for tailored interventions that consider specific demographic and clinical characteristics to improve mobility and stability in elderly individuals with hip osteoarthritis.

The observed discrepancies in stability and functional mobility between elderly individuals with hip osteoarthritis and age-matched asymptomatic controls can be attributed to the mechanical and neurological impairments that osteoarthritis induces (Steinhilber, 2012). Osteoarthritis is associated with joint degradation and inflammation, which lead to pain and muscular weakness, particularly affecting the stability of the lower extremities (Shorter et al., 2019). This degeneration and the accompanying pain reduce an individual’s ability to maintain balance and perform mobility-related tasks efficiently, as demonstrated by the marked reduction in stability across all directions and the slower TUG scores (Moutzouri, 2019). The greatest disparity observed in the forward direction might be due to the forward movement engaging major hip stabilizers, which are likely compromised in patients with hip osteoarthritis (Alkhamis et al., 2024). Additionally, the deterioration of proprioceptive feedback mechanisms, which are crucial for maintaining balance and coordinating movement, further exacerbates stability issues, leading to an overall decline in functional mobility (Henry and Baudry, 2019).

Previous studies corroborate these findings, highlighting the role of muscular weakness and joint instability in decreasing mobility (Ramirez et al., 2013; Bateni and Maki, 2005). According to Meyer et al. (2018), hip osteoarthritis significantly affects the hip abductors and flexors, which are essential for lateral and forward stability, respectively. Furthermore, research by Wojcieszek et al. (2022) emphasizes that chronic pain, a common symptom in osteoarthritis patients, directly correlates with reduced mobility and poorer quality of life, as pain limits the range of motion and the willingness to engage in physical activity (Wojcieszek et al., 2022). The work by Al-Mahrouqi et al. (2020) also supports the concept that a longer duration of osteoarthritis is associated with increased severity of mobility impairments, consistent with the moderation analysis results which indicated that the duration of osteoarthritis diagnosis influences stability and mobility outcomes (Al-Mahrouqi et al., 2020). Collectively, these studies validate the observed patterns in the current research, underscoring the profound impact of osteoarthritis on stability and functional mobility, and stressing the importance of early intervention to manage symptoms and enhance life quality for affected individuals (Al-Mahrouqi et al., 2020).

The significant correlation between stability limits and functional mobility in elderly individuals with hip osteoarthritis, as detailed in the analysis, can be attributed to the integral role that musculoskeletal stability plays in enabling effective and safe movement (Raizah et al., 2023). Increased stability, particularly in those suffering from joint degenerative conditions like osteoarthritis, helps in maintaining posture and balance which are crucial for functional mobility (Sziver et al., 2016). The observed correlations suggest that improvements in stability through therapeutic interventions might enhance the capacity for movement and reduce the risk of falls (Picorelli et al., 2018). The substantial positive correlations across various directions of stability measurement, especially in the total objective, highlight that overall stability is not merely about managing individual movements but is central to enhancing holistic mobility functions (Cook et al., 2014). Conversely, the TUG Score, reflecting inverse mobility (where lower scores indicate better mobility), aligns with these findings by showing a notable negative correlation with stability limits, confirming that increased bodily stability tends to improve mobility outcomes substantially (Clemens, 2017).

Supporting these observations, previous research underscores the connection between stability and functional mobility. For instance, studies by Hirase et al. (2020) have shown that joint stability is critically important for maintaining mobility in elderly individuals, particularly those with degenerative joint diseases. Similarly, Hoglund et al. (2018) reported that targeted interventions aiming to enhance musculoskeletal stability could lead to significant improvements in the overall functional mobility of patients with hip osteoarthritis. These studies corroborate the current findings, reinforcing the critical link between enhanced stability and improved functional mobility (Hoglund et al., 2018). Furthermore, the research by Calabrò et al. (2022) demonstrates that rehabilitative strategies focused on strengthening stabilizing muscles around the hip joint not only improve stability but also contribute positively to mobility outcomes, which is consistent with the negative correlation observed between the TUG Scores and stability limits in this study. This body of evidence supports the hypothesis that improving stability through specific therapeutic approaches can substantially enhance the mobility and quality of life for elderly individuals suffering from hip osteoarthritis (Atukorala and Hunter, 2023).

The moderation analysis underscores the complex interplay between demographic and clinical variables and their impact on stability and mobility among elderly individuals with hip osteoarthritis. Age and the duration of osteoarthritis diagnosis emerge as significant moderators, enhancing the association between stability and mobility. This suggests that as individuals age or live longer with osteoarthritis, their mobility and stability are increasingly affected, likely due to the progressive nature of joint degeneration which exacerbates functional decline (Ishijima et al., 2016). In contrast, while body mass index (BMI) also shows a moderate positive influence, indicating that higher BMI might exacerbate mobility issues, gender does not significantly alter this relationship (Kennedy et al., 1997). These findings align with previous research, such as that by Kadam and Croft (2007), who noted that increased age and chronicity of symptoms typically worsen mobility outcomes in osteoarthritic patients. Furthermore, studies by Chen et al. (2020) support the notion that higher BMI contributes to poorer joint function and mobility due to greater mechanical load on compromised joints. The absence of a significant gender effect might suggest that both sexes are equally susceptible to the biomechanical and symptomatic impacts of osteoarthritis on mobility and stability, which contrasts with some literature suggesting variations in disease impact and coping mechanisms between genders (Vincent and Mathews, 2013). This comprehensive analysis not only corroborates existing theories about osteoarthritis progression but also highlights the critical need for personalized management strategies that address these specific factors to optimize mobility and quality of life in this population (Maly et al., 2020).

This study, while providing valuable insights into the stability and mobility impairments in elderly individuals with hip osteoarthritis, is not without limitations. One of the primary constraints is the cross-sectional design, which, although effective for identifying associations at a specific point in time, does not allow for the determination of causality between osteoarthritis progression and mobility impairments. Additionally, the study relied on self-reported data for the duration of osteoarthritis diagnosis, which could introduce recall bias affecting the accuracy of the reported disease duration. Furthermore, the sample size, while adequate for detecting moderate effects, may not fully capture the variability and nuances of more subtle clinical differences within the population, particularly when analyzing the effects of demographic variables such as gender. The study also did not account for potential confounders like activity level or other comorbidities, which could influence mobility and stability independently of osteoarthritis. Future studies could benefit from a longitudinal design, larger and more diverse samples, and more comprehensive data collection strategies to address these limitations and enhance the understanding of the dynamics between osteoarthritis and functional mobility.

5 Conclusion

The study conclusively demonstrates that elderly individuals with hip osteoarthritis experience significant impairments in stability and functional mobility compared to age-matched asymptomatic controls, with stability strongly correlating with mobility outcomes. Moderation analysis further revealed that age and duration of osteoarthritis significantly influence the interplay between stability and mobility, suggesting that longer disease duration and advanced age exacerbate these impairments. Notably, body mass index also moderately affects mobility, whereas gender does not significantly impact the observed associations. These findings highlight the profound impact of hip osteoarthritis on the functional capabilities of the elderly, underscoring the necessity for targeted therapeutic interventions that prioritize stability enhancement to improve mobility and overall quality of life in this population. This research adds to the body of knowledge by quantitatively establishing the relationships between biomechanical stability, demographic factors, and mobility in individuals burdened by osteoarthritis, paving the way for more tailored and effective clinical management strategies.

Data availability statement

The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: https://doi.org/10.5281/zenodo.11382872.

Ethics statement

The studies involving humans were approved by King Khalid University Ethics Committee. The studies were conducted in accordance with the local legislation and institutional requirements. The participants provided their written informed consent to participate in this study.

Author contributions

KA: Conceptualization, Data curation, Formal Analysis, Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing–original draft, Writing–review and editing. RR: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Methodology, Software, Supervision, Writing–original draft, Writing–review and editing.

Funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was supported by Deanship of Scientific Research, King Khalid University - RGP. 2/23/45.

Acknowledgments

The authors extend their appreciation to the Deanship of Research and Graduate studies at King Khalid University for funding this work through a Large Research Group project under grant number RGP. 2/23/45.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

References

Abramoff, B., and Caldera, F. E. (2020). Osteoarthritis: pathology, diagnosis, and treatment options. Med. Clin. 104 (2), 293–311. doi:10.1016/j.mcna.2019.10.007

CrossRef Full Text | Google Scholar

Alkhamis, B. A., Reddy, R. S., Alahmari, K. A., Alshahrani, M. S., Koura, G. M., Ali, O. I., et al. (2024). Balancing act: unraveling the link between muscle strength, proprioception, and stability in unilateral hip osteoarthritis. Plos one 19 (2), e0298625. doi:10.1371/journal.pone.0298625

PubMed Abstract | CrossRef Full Text | Google Scholar

Al-Mahrouqi, M. M., Vicenzino, B., MacDonald, D. A., and Smith, M. D. (2020). Disability, physical impairments, and poor quality of life, rather than radiographic changes, are related to symptoms in individuals with ankle osteoarthritis: a cross-sectional laboratory study. J. Orthop. and Sports Phys. Ther. 50 (12), 711–722. doi:10.2519/jospt.2020.9376

CrossRef Full Text | Google Scholar

Atukorala, I., and Hunter, D. J. (2023). A review of quality-of-life in elderly osteoarthritis. Expert Rev. pharmacoeconomics and outcomes Res. 23 (4), 365–381. doi:10.1080/14737167.2023.2181791

CrossRef Full Text | Google Scholar

Bateni, H., and Maki, B. E. (2005). Assistive devices for balance and mobility: benefits, demands, and adverse consequences. Archives Phys. Med. rehabilitation 86 (1), 134–145. doi:10.1016/j.apmr.2004.04.023

CrossRef Full Text | Google Scholar

Batushansky, A., Zhu, S., Komaravolu, R. K., South, S., Mehta-D’souza, P., and Griffin, T. M. (2022). Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA. Osteoarthr. Cartil. 30 (4), 501–515. doi:10.1016/j.joca.2021.06.013

CrossRef Full Text | Google Scholar

Bergquist, R., Nerz, C., Taraldsen, K., Mellone, S., Ihlen, E. A., Vereijken, B., et al. (2020). Predicting advanced balance ability and mobility with an instrumented timed up and go test. Sensors 20 (17), 4987. doi:10.3390/s20174987

PubMed Abstract | CrossRef Full Text | Google Scholar

Boekesteijn, R. J., Smolders, J. M., Busch, V. J., Geurts, A. C., and Smulders, K. (2021). Independent and sensitive gait parameters for objective evaluation in knee and hip osteoarthritis using wearable sensors. BMC Musculoskelet. Disord. 22, 242–311. doi:10.1186/s12891-021-04074-2

PubMed Abstract | CrossRef Full Text | Google Scholar

Brembo, E. A. (2020). The hip journey: an exploration of needs, treatment decision-making and psychosocial predictors of surgical outcomes in patients with hip osteoarthritis.

Google Scholar

Calabrò, R. S., Billeri, L., Ciappina, F., Balletta, T., Porcari, B., Cannavò, A., et al. (2022). Toward improving functional recovery in spinal cord injury using robotics: a pilot study focusing on ankle rehabilitation. Expert Rev. Med. devices 19 (1), 83–95. doi:10.1080/17434440.2021.1894125

PubMed Abstract | CrossRef Full Text | Google Scholar

Cella, A., De Luca, A., Squeri, V., Parodi, S., Vallone, F., Giorgeschi, A., et al. (2020). Development and validation of a robotic multifactorial fall-risk predictive model: a one-year prospective study in community-dwelling older adults. PLoS One 15 (6), e0234904. doi:10.1371/journal.pone.0234904

PubMed Abstract | CrossRef Full Text | Google Scholar

Chen, L., Zheng, J. J. Y., Li, G., Yuan, J., Ebert, J. R., Li, H., et al. (2020). Pathogenesis and clinical management of obesity-related knee osteoarthritis: impact of mechanical loading. J. Orthop. Transl. 24, 66–75. doi:10.1016/j.jot.2020.05.001

CrossRef Full Text | Google Scholar

Clemens, S. M. (2017) “The development and use of the component timed-up-and-go test to determine,” in Basic prosthetic mobility in people with lower limb amputation. Florida: University of Miami.

Google Scholar

Cook, G., Burton, L., Hoogenboom, B. J., and Voight, M. (2014). Functional movement screening: the use of fundamental movements as an assessment of function-part 1. Int. J. sports Phys. Ther. 9 (3), 396–409.

PubMed Abstract | Google Scholar

De Jong, L., Van Dijsseldonk, R., Keijsers, N., and Groen, B. (2020). Test-retest reliability of stability outcome measures during treadmill walking in patients with balance problems and healthy controls. Gait and posture 76, 92–97. doi:10.1016/j.gaitpost.2019.10.033

PubMed Abstract | CrossRef Full Text | Google Scholar

Do, K., and Yim, J. (2020). Effects of muscle strengthening around the hip on pain, physical function, and gait in elderly patients with total knee arthroplasty: a randomized controlled trial. Healthcare 489, 489. doi:10.3390/healthcare8040489

PubMed Abstract | CrossRef Full Text | Google Scholar

Egerton, T., Nelligan, R. K., Setchell, J., Atkins, L., and Bennell, K. L. (2018). General practitioners’ views on managing knee osteoarthritis: a thematic analysis of factors influencing clinical practice guideline implementation in primary care. BMC Rheumatol. 2, 30–11. doi:10.1186/s41927-018-0037-4

PubMed Abstract | CrossRef Full Text | Google Scholar

Fonseca, P., Sousa, M., Sebastião, R., Goethel, M., Barralon, P., Idigoras, I., et al. (2021). Equimetrix device: criteria based validation and reliability analysis of the center of mass and base of support of a human postural assessment system. Sensors 21 (2), 374. doi:10.3390/s21020374

PubMed Abstract | CrossRef Full Text | Google Scholar

Grabiner, M. D., and Kaufman, K. (2021). Developing and establishing biomechanical variables as risk biomarkers for preventable gait-related falls and assessment of intervention effectiveness. Front. sports Act. living 3, 722363. doi:10.3389/fspor.2021.722363

PubMed Abstract | CrossRef Full Text | Google Scholar

Henry, M., and Baudry, S. (2019). Age-related changes in leg proprioception: implications for postural control. J. neurophysiology 122 (2), 525–538. doi:10.1152/jn.00067.2019

PubMed Abstract | CrossRef Full Text | Google Scholar

Hirase, T., Okubo, Y., Sturnieks, D. L., and Lord, S. R. (2020). Pain is associated with poor balance in community-dwelling older adults: a systematic review and meta-analysis. J. Am. Med. Dir. Assoc. 21 (5), 597–603. doi:10.1016/j.jamda.2020.02.011

PubMed Abstract | CrossRef Full Text | Google Scholar

Hoglund, L. T., Pontiggia, L., and Kelly, J. D. (2018). A 6-week hip muscle strengthening and lumbopelvic-hip core stabilization program to improve pain, function, and quality of life in persons with patellofemoral osteoarthritis: a feasibility pilot study. Pilot Feasibility Stud. 4, 70–14. doi:10.1186/s40814-018-0262-z

PubMed Abstract | CrossRef Full Text | Google Scholar

Ishijima, M., Kaneko, H., Hada, S., Kinoshita, M., Sadatsuki, R., Liu, L., et al. (2016). Osteoarthritis as a cause of locomotive syndrome: its influence on functional mobility and activities of daily living. Clin. Rev. Bone Mineral Metabolism 14, 77–104. doi:10.1007/s12018-016-9212-6

CrossRef Full Text | Google Scholar

Jie, F., Zhong-Lin, Y., Dong-Mei, L., and Ni-Ni, L. (2015). Moderation effect analysis based multiple linear regression. J. Psychol. Sci. (3), 715.

Google Scholar

Kadam, U. T., and Croft, P. R. (2007). Clinical comorbidity in osteoarthritis: associations with physical function in older patients in family practice. J. rheumatology 34 (9), 1899–1904.

Google Scholar

Kennedy, A., Gettys, T. W., Watson, P., Wallace, P., Ganaway, E., Pan, Q., et al. (1997). The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure. J. Clin. Endocrinol. and Metabolism 82 (4), 1293–1300. doi:10.1210/jcem.82.4.3859

CrossRef Full Text | Google Scholar

Laitner, M. H., Erickson, L. C., SfWsHR, O., Group, C. P. W., and Ortman, E. (2021). Understanding the impact of sex and gender in osteoarthritis: assessing research gaps and unmet needs. J. Women's Health 30 (5), 634–641. doi:10.1089/jwh.2020.8828

CrossRef Full Text | Google Scholar

Litwic, A., Edwards, M. H., Dennison, E. M., and Cooper, C. (2013). Epidemiology and burden of osteoarthritis. Br. Med. Bull. 105 (1), 185–199. doi:10.1093/bmb/lds038

PubMed Abstract | CrossRef Full Text | Google Scholar

Maly, M., Marriott, K., and Chopp-Hurley, J. (2020). Osteoarthritis year in review 2019: rehabilitation and outcomes. Osteoarthr. Cartil. 28 (3), 249–266. doi:10.1016/j.joca.2019.11.008

CrossRef Full Text | Google Scholar

Meyer, C. A., Wesseling, M., Corten, K., Nieuwenhuys, A., Monari, D., Simon, J.-P., et al. (2018). Hip movement pathomechanics of patients with hip osteoarthritis aim at reducing hip joint loading on the osteoarthritic side. Gait and Posture 59, 11–17. doi:10.1016/j.gaitpost.2017.09.020

PubMed Abstract | CrossRef Full Text | Google Scholar

Moutzouri, M. (2019). The effects of enhanced sensori-motor rehabilitation on indices of functional performance in patients undergoing total knee replacement.

Google Scholar

Murphy, N. J., Eyles, J. P., and Hunter, D. J. (2016). Hip osteoarthritis: etiopathogenesis and implications for management. Adv. Ther. 33, 1921–1946. doi:10.1007/s12325-016-0409-3

PubMed Abstract | CrossRef Full Text | Google Scholar

Nolff, M. R., Kapur, S., Kendall, B. J., Doumas, M., Conner, N. O., Chander, H., et al. (2024). An initial set of reference values for the Balance Tracking System (BTrackS) Limits of Stability protocol. Gait and Posture 107, 67–71. doi:10.1016/j.gaitpost.2023.09.008

PubMed Abstract | CrossRef Full Text | Google Scholar

Palm, H.-G., Lang, P., Strobel, J., Riesner, H.-J., and Friemert, B. (2014). Computerized dynamic posturography: the influence of platform stability on postural control. Am. J. Phys. Med. and rehabilitation 93 (1), 49–55. doi:10.1097/phm.0b013e3182a39019

CrossRef Full Text | Google Scholar

Picorelli, A. M., Hatton, A. L., Gane, E. M., and Smith, M. D. (2018). Balance performance in older adults with hip osteoarthritis: a systematic review. Gait and posture 65, 89–99. doi:10.1016/j.gaitpost.2018.07.001

PubMed Abstract | CrossRef Full Text | Google Scholar

Raizah, A., Reddy, R. S., Alshahrani, M. S., Tedla, J. S., Dixit, S., Gular, K., et al. (2023). Investigating knee joint proprioception and its impact on limits of stability using dynamic posturography in individuals with bilateral knee osteoarthritis—a cross-sectional study of comparisons and correlations. J. Clin. Med. 12 (8), 2764. doi:10.3390/jcm12082764

PubMed Abstract | CrossRef Full Text | Google Scholar

Ramirez, D. S., van der Leeden, M., Knol, D. L., van der Esch, M., Roorda, L. D., Verschueren, S., et al. (2013). Association of postural control with muscle strength, proprioception, self-reported knee instability and activity limitations in patients with knee osteoarthritis. J. rehabilitation Med. 45 (2), 192–197. doi:10.2340/16501977-1087

CrossRef Full Text | Google Scholar

Rose, D. J., Jones, C. J., and Lucchese, N. (2002). Predicting the probability of falls in community-residing older adults using the 8-foot up-and-go: a new measure of functional mobility. J. aging Phys. activity 10 (4), 466–475. doi:10.1123/japa.10.4.466

CrossRef Full Text | Google Scholar

Shorter, E., Sannicandro, A. J., Poulet, B., and Goljanek-Whysall, K. (2019). Skeletal muscle wasting and its relationship with osteoarthritis: a mini-review of mechanisms and current interventions. Curr. Rheumatol. Rep. 21, 40–48. doi:10.1007/s11926-019-0839-4

PubMed Abstract | CrossRef Full Text | Google Scholar

Srinivasan, R., Lohith, C., Srinivasan, R., and Lohith, C. (2017). Main study—detailed statistical analysis by multiple regression. Strategic Mark. innovation Indian MSMEs, 69–92. doi:10.1007/978-981-10-3590-6_9

CrossRef Full Text | Google Scholar

Steinhilber, B. (2012). Hip muscle strength in patients with osteoarthritis of the hip: aspects of the reproducibility of measurement, training and its relevance to self-reported physical function.

Google Scholar

Sturnieks, D. L. (2021). Biomechanics of balance and falling. Falls Older People Risk Factors, Strategies Prev. Implic. Pract., 105–118. doi:10.1017/9781108594455.006

CrossRef Full Text | Google Scholar

Sziver, E., Nagy, E., Preszner-Domján, A., Pósa, G., Horvath, G., Balog, A., et al. (2016). Postural control in degenerative diseases of the hip joint. Clin. Biomech. 35, 1–6. doi:10.1016/j.clinbiomech.2016.04.001

CrossRef Full Text | Google Scholar

Tornero-Quiñones, I., Sáez-Padilla, J., Espina Díaz, A., Abad Robles, M. T., and Sierra Robles, Á. (2020). Functional ability, frailty and risk of falls in the elderly: relations with autonomy in daily living. Int. J. Environ. Res. public health 17 (3), 1006. doi:10.3390/ijerph17031006

PubMed Abstract | CrossRef Full Text | Google Scholar

van Doormaal, M. C., Meerhoff, G. A., Vliet Vlieland, T. P., and Peter, W. F. (2020). A clinical practice guideline for physical therapy in patients with hip or knee osteoarthritis. Musculoskelet. care 18 (4), 575–595. doi:10.1002/msc.1492

CrossRef Full Text | Google Scholar

Vincent, H. K., and Mathews, A. (2013). Obesity and mobility in advancing age: mechanisms and interventions to preserve independent mobility. Curr. Obes. Rep. 2, 275–283. doi:10.1007/s13679-013-0059-6

CrossRef Full Text | Google Scholar

Wilson, J. A., and Kobsar, D. (2021). Osteoarthritis year in review 2020: mechanics. Osteoarthr. Cartil. 29 (2), 161–169. doi:10.1016/j.joca.2020.12.009

CrossRef Full Text | Google Scholar

Wojcieszek, A., Kurowska, A., Majda, A., Liszka, H., and Gądek, A. (2022). The impact of chronic pain, stiffness and difficulties in performing daily activities on the quality of life of older patients with knee osteoarthritis. Int. J. Environ. Res. public health 19 (24), 16815. doi:10.3390/ijerph192416815

PubMed Abstract | CrossRef Full Text | Google Scholar

Keywords: hip osteoarthritis, limits of stability, functional mobility, elderly, posturography

Citation: Alahmari KA and Reddy RS (2024) Biomechanical analysis of limits of stability using computerized posturography: correlations with functional mobility in elderly individuals with hip osteoarthritis – a cross-sectional study. Front. Bioeng. Biotechnol. 12:1440393. doi: 10.3389/fbioe.2024.1440393

Received: 29 May 2024; Accepted: 13 November 2024;
Published: 25 November 2024.

Edited by:

Vincenzo Bonaiuto, University of Rome Tor Vergata, Italy

Reviewed by:

Massimiliano Mangone, Sapienza University of Rome, Italy
Oskar Rosiak, Polish Mother’s Memorial Hospital Research Institute, Poland

Copyright © 2024 Alahmari and Reddy. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Ravi Shankar Reddy, cnNoYW5rYXJAa2t1LmVkdS5zYQ==

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.