Peptide-Enriched Silk Fibroin Sponge and Trabecular Titanium Composites to Enhance Bone Ingrowth of Prosthetic Implants in an Ovine Model of Bone Gaps
- 1Laboratório de Biologia das Interações Celulares, Departamento de Morfologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
- 2Laboratório de Pesquisas Clínicas, Programa de Pós-Graduação de Ciências Farmacêuticas, Universidade Federal de Ouro Preto, Ouro Preto, Brazil
- 3Laboratório de Biomateriais e Patologia Experimental, Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Ouro Preto, Brazil
- 4Grupo de Pesquisa em Imunologia Celular e Molecular, Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil
- 5Grupo Integrado de Pesquisas em Biomarcadores, Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil
- 6Departamento de Medicina, Universidade José Rosário Vellano, Belo Horizonte, Brazil
by Lanna, M. F., Resende, L. A., Aguiar-Soares, R. D. O., de Miranda, M. B., de Mendonça, L. Z., Melo Júnior, O. A. O., et al. (2020). Front. Bioeng. Biotechnol. 8:538203. doi: 10.3389/fbioe.2020.538203
In the original article, there was an error. We incorrectly referenced the sponge as being associated to “Vitafoam Ltd., Manchester, United Kingdom.” The correct reference is “Rei das Espumas, Belo Horizonte, Brazil.”
A correction has been made to the Materials and Methods, subsection Sponge Implants paragraph one:
Disk-shaped (4 mm × 8 mm) polyether-polyurethane sponges (Rei das Espumas, Belo Horizonte, Brazil) were soaked overnight in 70% v/v ethanol and boiled in distilled water for 15 min prior to implantation. Mice were anesthetized by intra-peritoneal injection of ketamine (150 mg kg−1) plus xylazine (10 mg kg−1) and the dorsal fur shaved and the skin wiped with 70% v/v ethanol. The sponge disks were subcutaneously implanted throughout a 1-cm long dorsal mid-line incision and the animals were monitored daily for discomfort/distress or any signs of opportunistic infection. Sponge implants were removed for histological/morphometric analysis, flow cytometry, immunophenotyping, and soluble cytokine measurements at Day5, Day6, Day7, Day10, and Day14 after implantation. The compendium of the experimental design, study groups, timeline, and illustrated images of sponge implants are provided in Figure 1.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: sponge implant model, biomolecules screening, dynamics of phenotypic and functional features, immunophenotyping, cytokines
Citation: Lanna MF, Resende LA, Aguiar-Soares RDO, de Miranda MB, de Mendonça LZ, Melo Júnior OAO, Mariano RMS, Leite JC, Silveira P, Corrêa-Oliveira R, Dutra WO, Reis AB, Martins-Filho OA, de Moura SAL, Silveira-Lemos D and Giunchetti RC (2021) Corrigendum: Kinetics of Phenotypic and Functional Changes in Mouse Models of Sponge Implants: Rational Selection to Optimize Protocols for Specific Biomolecules Screening Purposes. Front. Bioeng. Biotechnol. 9:660117. doi: 10.3389/fbioe.2021.660117
Received: 28 January 2021; Accepted: 03 February 2021;
Published: 03 March 2021.
Copyright © 2021 Lanna, Resende, Aguiar-Soares, de Miranda, de Mendonça, Melo Júnior, Mariano, Leite, Silveira, Corrêa-Oliveira, Dutra, Reis, Martins-Filho, de Moura, Silveira-Lemos and Giunchetti. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Denise Silveira-Lemos, ZGVuaXNlLmxlbW9zJiN4MDAwNDA7Z21haWwuY29t