Corrigendum: AFAP1-AS1 Promotes Epithelial-Mesenchymal Transition and Tumorigenesis Through Wnt/β-Catenin Signaling Pathway in Triple-Negative Breast Cancer

A Corrigendum On
AFAP1-AS1 Promotes Epithelial-Mesenchymal Transition and Tumorigenesis Through Wnt/β-Catenin Signaling Pathway in Triple-Negative Breast Cancer

by Zhang K, Liu P, Tang H, Xie X, Kong Y, Song C, Qiu X, Xiao X (2018). Front. Pharmacol. 9:1248. doi: 10.3389/fphar.2018.01248

In the original article, there was a mistake in the legend for Figure 4 as published. We performed Wound-healing assay and Transwell invasion assay using MDA-MB-231 cells, but we made a mistake statement that using MDA-MB-231 and BT-549 cells. The correct legend appears below.

“AFAP1-AS1 knockdown inhibited cell invasion and migration. (A) Wound-healing assay was used to measure cell migration. These pictures show that cell migration of TNBC cells was significantly inhibited in AFAP1-AS1 knockdown groups. (B) Transwell invasion assay was used to measure cell invasion of MDA-MB-231 cells transfected with siRNA-ctr, siRNA#1, or siRNA#2 (**P < 0.01). The representative data from three independent experiments are shown”.

In the original article, there was a mistake in Figure 4 as published. We performed Wound-healing assay and Transwell invasion assay using MDA-MB-231 cells. Due to our mistake, the photographs of Wound-healing assay in MDA-MB-231 cells were mistaken for the photographs of BT-549 cells and uploaded to Figure 4. The corrected Figure 4 appears below.

In the original article, there was a mistake in Figure 6 as published. Due to our mistake, the IHC images of snail which were photographed in repeated experiments were mistakenly uploaded as the IHC images of β-catenin in the si-ctr group. The corrected Figure 6 appears below.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

FIGURE 4

Figure 4 AFAP1-AS1 knockdown inhibited cell invasion and migration. (A) Wound-healing assay was used to measure cell migration. These pictures show that cell migration of TNBC cells was significantly inhibited in AFAP1-AS1 knockdown groups. (B) Transwell invasion assay was used to measure cell invasion of MDA-MB-231 cells transfected with siRNA-ctr, siRNA#1, or siRNA#2 (**P < 0.01). The representative data from three independent experiments are shown.

FIGURE 6

Figure 6 Immunohistochemistry assay of b-catenin, SLUG, and SNAIL expressions in TNBC tissues. b-catenin, SLUG, and SNAIL expressions were positive in TNBC tissues without AFAP1-AS1 downregulation, while b-catenin, SLUG, and SNAIL expressions were negative in AFAP1-AS1 knockdown TNBC tissues.