In the original article, there was a mistake in Figure 1 as published. We used the Volcano Plot, which was automatically generated using the Expression Suite v1.0.3 software (Thermo Fisher Scientific). This software visualizes the p-values and fold change values after each qRT-PCR run. A log2 (Fold Change) greater than or equal to one, is the standard boundary field.
Therefore, targets with a fold less than the lower boundary were automatically colored in green. However, as stated in the article, according to published guidelines, we validated the miRNAs with p-values < 0.05 (dot over the blue line) independently from their fold change. We have therefore adjusted the representation in the figure to avoid confusion.
The corrected Figure 1 appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Figure 1
Summary
Keywords
sporadic amyotrophic lateral sclerosis, microRNA, target genes, peripheral blood markers, high throughput next-generation sequencing (HT-NGS), clinical parameters, bioinformatics, pathway analysis
Citation
Liguori M, Nuzziello N, Introna A, Consiglio A, Licciulli F, D'Errico E, Scarafino A, Distaso E and Simone IL (2019) Corrigendum: Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis. Front. Mol. Neurosci. 11:488. doi: 10.3389/fnmol.2018.00488
Received
30 November 2018
Accepted
14 December 2018
Published
10 January 2019
Volume
11 - 2018
Edited and reviewed by
Giuseppe Filomeni, Danish Cancer Society, Denmark
Updates
Copyright
© 2019 Liguori, Nuzziello, Introna, Consiglio, Licciulli, D'Errico, Scarafino, Distaso and Simone.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Maria Liguori maria.liguori@cnr.it;maria.liguori@ba.itb.cnr.it
†These authors have contributed equally to this work
Disclaimer
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