The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat
- 1MTA-SZTE Neuroscience Research Group, University of Szeged, Szeged, Hungary
- 2Faculty of Health Sciences and Social Studies, University of Szeged, Szeged, Hungary
- 3Department of Neurology, Faculty of Medicine, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary
A Corrigendum on
The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat
by Nagy-Grócz, G., Laborc, K. F., Veres, G., Bajtai, A., Bohár, Z., Zádori, D., et al. (2017). Front. Neurol. 8:278. doi: 10.3389/fneur.2017.00278
In the original article, there was a mistake in Figures 2, 3, and 5 as published. The authors became aware of the erroneous representation of the loading controls for the western blots of the figures. These errors were due to mistakes while generating the figures from templates of the western blot X-ray film images. The corrected Figures 2, 3, and 5 appear below.
Figure 2. Western blot analysis of TDO2 and GAPDH protein from the TNC. The quantitative analysis shows that in the NTG group the relative optical density of TDO2 specific bands were significantly less pronounced compared with the placebo group. *p < 0.05; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; NTG, nitroglycerin; TDO2, tryptophan 2,3-dioxygenase 2; TNC, caudal trigeminal nucleus.
Figure 3. Western blot of IDO1 and GAPDH expression in the TNC. The quantitative analysis shows that in the NTG group, the relative optical density of IDO1-specific bands was significantly decreased compared with the placebo group. *p < 0.05; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IDO1, indoleamine 2,3-dioxygenase; NTG, nitroglycerin; TNC, caudal trigeminal nucleus.
Figure 5. Illustrative Western blot bands and diagram of KMO and GAPDH in the TNC. The quantitative analysis shows that in the NTG group, the relative optical density of KMO specific bands was significantly weaker compared with the placebo group. *p < 0.05; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; KMO, L-kynurenine 3-monooxygenase; NTG, nitroglycerin; TNC, caudal trigeminal nucleus.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.
Keywords: migraine, nitroglycerin, kynurenic acid, L-kynurenine, kynurenine pathway
Citation: Nagy-Grócz G, Laborc KF, Veres G, Bajtai A, Bohár Z, Zádori D, Fejes-Szabó A, Spekker E, Vécsei L and Párdutz Á (2020) Corrigendum: The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat. Front. Neurol. 11:1049. doi: 10.3389/fneur.2020.01049
Received: 08 May 2020; Accepted: 10 August 2020;
Published: 24 September 2020.
Edited and reviewed by: Milena De Felice, The University of Sheffield, United Kingdom
Copyright © 2020 Nagy-Grócz, Laborc, Veres, Bajtai, Bohár, Zádori, Fejes-Szabó, Spekker, Vécsei and Párdutz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: László Vécsei, vecsei.laszlo@med.u-szeged.hu