Addendum: A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T&gt;C Mutation in the Mitochondrial MTND3 Gene

Li, Tao-Ran; Wang, Qun; Liu, Mao-Mao; Lv, Rui-Juan

doi:10.3389/fneur.2019.00936

CORRECTION article

Front. Neurol. , 18 September 2019

Sec. Neurogenetics

Volume 10 - 2019 | https://doi.org/10.3389/fneur.2019.00936

Addendum: A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene

This article is a correction to:

A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene
1. Read original article

$\nTao-Ran Li,$ Tao-Ran Li^1,2

Qun Wang¹

Mao-Mao Liu¹

Rui-Juan Lv¹^*

¹Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Beijing, China
²Department of Neurology, XuanWu Hospital of Capital Medical University, Beijing, China

An Addendum on
A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene

by Li, T.-R., Wang, Q., Liu, M.-M., and Lv, R.-J. (2019). Front. Neurol. 10:347. doi: 10.3389/fneur.2019.00347

In the original article, there was an error. There were two spelling mistakes in the article.

A correction has been made to Discussion and Conclusion, last sentence of Paragraph 8:

“Recognition of the characteristics of these patients with the T10191C mutation will help us improve the clinical understanding of LS or Leigh-like syndrome.”

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Addendum

In the original article, we had not obtained the heteroplasmy levels of the proband and her aunt from the gene sequencing company at the time of manuscript publication.

Through follow-up research, we make the following addendum:

By detecting the proband's and her aunt's blood sample, we found the heteroplasmy level of the proband is 33.2% (forward percent) or 38.2% (reverse percent) respectively, the heteroplasmy level of her aunt is 4.4% (forward percent) or 4.8% (reverse percent), respectively.

Keywords: Leigh syndrome, Leigh-like syndrome, MELAS, MELAS-LS overlap syndrome, m.10191T>C mutation

Citation: Li T-R, Wang Q, Liu M-M and Lv R-J (2019) Addendum: A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene. Front. Neurol. 10:936. doi: 10.3389/fneur.2019.00936

Received: 31 May 2019; Accepted: 12 August 2019;
Published: 18 September 2019.

Edited and reviewed by: Christos Proukakis, University College London, United Kingdom

Copyright © 2019 Li, Wang, Liu and Lv. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Rui-Juan Lv, bHZydWlqdWFuMTk4MUAxMjYuY29t

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Addendum: A Chinese Family With Adult-Onset Leigh-Like Syndrome Caused by the Heteroplasmic m.10191T>C Mutation in the Mitochondrial MTND3 Gene

Addendum

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