Graziano Pinna
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- Department of Psychiatry, The Psychiatric Institute, University of Illinois at Chicago, Chicago, IL, United States
A Corrigendum on
Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next?
by Pinna, G. (2020). Front. Endocrinol. 11:236. doi: 10.3389/fendo.2020.00236
In the original article, there was an error. “Allopregnanolone, today best known as brexanolone and marketed as Zulresso™ for the treatment of postpartum depression is part of only two recently Food and Drug Administration (FDA)-approved fast-acting antidepressants, with esketamine nasal spray, an NMDA receptor antagonist used in treatment-resistant depression with suicidality being the other.” However, SPRAVATO® (esketamine) CIII Nasal Spray was approved by the FDA last year to treat treatment-resistant depression in adults when used along with an oral antidepressant, and is not indicated for the treatment of suicidality.
A correction has been made to the Introduction section, First paragraph:
“Allopregnanolone, today best known as brexanolone and marketed as Zulresso™ for the treatment of postpartum depression is part of only two recently Food and Drug Administration (FDA)-approved fast-acting antidepressants, with esketamine nasal spray, an NMDA receptor antagonist used in treatment-resistant depression being the other (1).”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: brexanolone, allopregnanolone (3α, 5α-THP), postpartum depression, fast-acting antidepressant, GABAA receptor, 5α-reduced steroids, 5α-reductase, 3α-HSD
Citation: Pinna G (2020) Corrigendum: Allopregnanolone, the Neuromodulator Turned Therapeutic Agent: Thank You, Next? Front. Endocrinol. 11:507. doi: 10.3389/fendo.2020.00507
Received: 11 June 2020; Accepted: 24 June 2020;
Published: 30 July 2020.
Approved by:
Hubert Vaudry, Université de Rouen, FranceCopyright © 2020 Pinna. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Graziano Pinna, Z3Bpbm5hQHVpYy5lZHU=; Z3Jhemlhbm9fcGlubmFAeWFob28uY29t