Keywords: Frontiers in Neuroscience, Â Focused Review, Â Commentary, Â Grand Challenge, Â Theme, Â Depression, Â Drugs, Â DBS, Â Hypnosis, Â Neurogenesis, Â Postpartum Depression, Â Unipolar/Bipolar Depression, Â Serotonin, Â Glia, Â Brain Stimulation, Â Impact on Families and Society