FEATURED
Joseph Manuppello,
Jan Willem Van Der Laan,
Federica Madia
Frontiers Media SA
Carcinogenicity to rats and mice is evaluated for substances to which humans are exposed, including pharmaceuticals, agrochemicals, and industrial chemicals. For pharmaceuticals, recent efforts to...
Science
Toxicology
Regulatory Toxicology
Keywords: Animal Testing Alternatives,replacement,refinement,Reduction,biomarkers,tumor,Carcinogenicity Tests,Investigational New Drug Application,Neoplasms,Rodent bioassay,Chronic toxicity tests,Weight of evidence,WoE