Repurposed Drugs Targeting Cancer Signaling Pathways: Clinical Insights to Improve Oncologic Therapies, volume II

Gerardo Leyva-Gómez, Teresita Padilla-Benavides, Alma D. Campos-Parra

Frontiers Media SA

The field of drug development is a time-consuming and costly process, with the development of...

Health Oncology Molecular and Cellular Oncology

Keywords: Drug Repositioning,­Cancer,­Signaling Pathways,­treatments

Investigating the Interplay Between Tumor Mutations, Immune Evasion, and Targeted Therapy Resistance

Shanye Yin, Guangchuang Yu, Yinghao Wu

Frontiers Media SA

The field of cancer research has been significantly focused on understanding the complex interplay...

Health Oncology Molecular and Cellular Oncology

Keywords: tumor mutations,­Immune Evasion,­Targeted therapy resistance,­tumor heterogeneity,­Tumor Microenvironment,­Cancer Progression,­tumor-associated neoantigens

Deciphering the Role of Signature Genes in Cancer Prognosis and Therapy Resistance

Dalila Luciola Zanette, Manoj K. Pandey, Jawed A. Siddiqui

Frontiers Media SA

The field of signature genes in cancer prognosis and therapy resistance is pivotal in the...

Health Oncology Molecular and Cellular Oncology

Keywords: Gene expression signature,­tumor molecular subtypes,­molecular pathways,­resistance mechanisms,­targeted therapy

Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment

Ruowen Zhang, XiuJuan Qu, Yu Zhang

Frontiers Media SA

Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other...

Health Oncology Molecular and Cellular Oncology

Keywords: gastrointestinal cancer,­molecular oncology,­metastasis,­therapeutic resistance,­Novel therapy

Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment

Ruowen Zhang, XiuJuan Qu, Yu Zhang

Frontiers Media SA

Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other...

Health Oncology Molecular and Cellular Oncology

Keywords: gastrointestinal cancer,­molecular oncology,­metastasis,­therapeutic resistance,­Novel therapy

Evolutionary Biology of Tumor Initiation and Progression

Yusuke Suenaga, Erich Bornberg-Bauer, Mamoru Kato

Frontiers Media SA

Cancer is characterized by heterogeneous cells with capacity for self renewal, and selective...

Health Oncology Molecular and Cellular Oncology

Keywords: cancer evolution,­cancer heterogeneity,­Comparative Oncology,­cancer immunity,­Cancer genomics,­de novo evolved gene,­single-cell sequencing

New Insights into Fibrotic Signaling in Cancer

Patrick Ming-Kuen Tang, Eric W-F Lam, Francis Jay Mussai, Dongmei Zhang, Chunjie Li

Frontiers Media SA

Cancer is still a top leading cause of death worldwide. Ineffective treatments, severe side...

Health Oncology Molecular and Cellular Oncology

Diagnostic, Prognostic and Predictive Factors of Response in the Era of Precision Oncology in Breast Cancer

Francesco Schettini, Daniele Generali

Frontiers Media SA

In the last couple of decades, the study of the cancer genome and the progressive implementation of...

Health Oncology Molecular and Cellular Oncology

Keywords: breast cancer,­biomarker,­Intrinsic subtypes,­mutations,­predictive,­prognostic,­precision medicine,­precision oncology

New Therapeutics for Soft Tissue Sarcomas

Marla Weetall, Brian Van Tine, Matthew Ingham

Frontiers Media SA

Health Oncology Molecular and Cellular Oncology

Keywords: Sarcoma,­Therapeutics,­chemotherapy,­Animal Models,­biomarkers