Monoclonal Antibodies and Immune Checkpoint Inhibitors in the treatment of Cancer

Prakash Radhakrishnan, Cory L. Brooks, Murali M. Yallapu

Frontiers Media SA

Cancer is a complex disease that can evade the immune system's natural defenses. However, recent...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: Antibodies,­Immunotherapy,­MABR,­immune checkpoint inhibitors

Spotlighting the Interaction Network of Hub Genes, Molecules, and Cells in the Tumor Immune Microenvironment (TIME) and their Contribution to Malignant Progression

Xuanbin Wang, Yongqian Shu, Xiaoqiang Qi, Run Shi

Frontiers Media SA

The tumor immune microenvironment (TIME) is a complex network of interactions between cancer cells,...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: tumor immune microenvironment (TIME),­interaction network,­Immune Activation and Evasion,­therapeutic targets,­precision medicine,­Translational research

Cell Death in Cancer Immunology

Laura Senovilla, Laura Mondragón Martínez, Shensi Shen

Frontiers Media SA

The relationship between cell death and cancer immunology has been addressed for decades with...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Cell Death,­Oncoimmunology,­Cancer,­immunology,­cancer immunotherapy

Application of Multi-omics Analysis in Thoracic Cancer Immunotherapy

Attila Szöllősi, Hailin Tang, Yuan Li, Jindong Xie

Frontiers Media SA

Based on statistical data provided by the World Health Organization, cancer is widely acknowledged...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: multi-omics,­Thoracic cancer,­Immunotherapy,­oncology,­Tumor Microenvironment

Cancer Immunotherapy – Diagnostic and Therapeutic Strategies to Enhance Antitumoral Efficacies whilst Minimizing Toxicity

Roza Nurieva, Sang T. Kim, Yeonseok Chung

Frontiers Media SA

With their unprecedented success, cancer immunotherapies including immune checkpoint inhibitors...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy,­Resistance to immunotherapy,­immune checkpoint inhibitors,­Immune-related adverse events

Tumor Microenvironment and Metabolic Reprogramming in Cancer

Wei Chong, Hao Chen, Houjuan Zhu, Asif Raza, Yiju Wei

Frontiers Media SA

Metabolic reprogramming is the hallmark of malignant tumors. Both metabolic phenotype and metabolic...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Cancer,­Tumor Microenvironment,­metabolic reprogramming,­Metabolic characteristics,­immune response

Genetic and Epigenetic Control on Immune Responses Regulating Molecules in Cancer Development, Progression, and Treatment

Katherine Chiappinelli, Alejandro Villagra, Lidia Karabon

Frontiers Media SA

In line with recent evidence, the development of cancer has been described as uncontrolled cell...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immune regulatory molecules,­Genetic polymorphisms,­Cancer

Vector-based Cancer Immunotherapy

Björn L. Frendéus, Yaohe Wang, Ine Lentacker, Monika Semmrich

Frontiers Media SA

Immunotherapy is a clinically proven concept to prevent and treat diverse diseases. Therapeutic...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Vector,­cancer immunotherapy,­Anti tumour,­T cell,­mRNA vectors

Implications of Immune Landscape in Tumor Microenvironment

Selvarangan Ponnazhagan, Juana Serrano Lopez, Somchai Chutipongtanate

Frontiers Media SA

Tumor microenvironment (TME) plays an important role in immunosuppressive mechanisms that result in...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Tumor-immune,­stromal landscape,­Spatial transcriptomics,­Epigenetic mechanisms regulating immune suppression,­extracellular vesicles,­Immune checkpoint blockade,­Next generation tools