Immune system disorders: from molecular mechanisms to clinical implications

Mauricio César De Marzi, Marisa Mariel Fernandez, Ruben Dario Motrich, Matias Ostrowski

Frontiers Media SA

In recent years, the increase in knowledge about the functioning of the immune system has revealed...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Immune system disorders,­dysfunction,­Autoimmune Diseases,­Autoinflammatory diseases,­immunodeficiency,­Immunosuppression,­immune therapy,­Immune Modulation

Prognostic and Predictive Factors in Autoimmune Connective Tissue Disorders

Francesca Wanda Rossi, Mohammed Osman, Ilaria Mormile

Frontiers Media SA

Autoimmune connective tissue diseases, including systemic lupus erythematosus, Sjögren’s syndrome,...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Adaptive Immunity,­innate immunity,­Inflammation,­Connective tissue disorders,­biomarkers,­Autoimmunity,­Autoimmune Diseases,­connective tissue disorders.

Single-cell analysis on the pathophysiology of autoimmune diseases

Shiang-Jong Tzeng, InKyeom Kim, Kuang-Hui Sun

Frontiers Media SA

Despite increasing research to facilitate the understanding of the pathophysiology of autoimmune...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: autoimmune disease,­single-cell RNA sequencing (scRNA-seq),­single cell,­spatial,­tran

Pemphigus and pemphigoid diseases: in memoriam Detlef Zillikens

Ralf J. Ludwig, Frédéric Caux, Christian David Sadik, Enno Schmidt, Dedee Murrell, Takashi Hashimoto, Aimee S. Payne

Frontiers Media SA

Pemphigus and pemphigoid diseases are a heterogenous group of autoimmune blistering disorders...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Pemphigoid,­Pemphigus,­Autoantibody,­desmosome,­hemidesmosome,­desmoglein,­BP180,­Type VII collagen,­Laminin 332,­BP230,­diagnosis,­Treatment,­mouse model

Emerging molecular mechanisms and therapeutics of autoimmune liver or kidney diseases

Jiabo Wang, Zhengsheng Zou, Dandan Lin, Ying Sun, Weici Zhang, Zhaofang Bai, Guang Xu

Frontiers Media SA

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Liver Diseases,­Autoimmune,­Kidney Diseases

The gut-immune axis: A complex training ground impacting inflammatory pathologies

Jose Garrido-Mesa, Julio Galvez, Natividad Garrido Mesa

Frontiers Media SA

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: gut,­Inflammation,­Functional Genomics,­immune repertoire,­Innate immune training,­microbiome,­Intestinal Homeostasis,­leaky gut,­Hygiene Hypothesis,­Immunomodulation,­Immune trafficking

Rare immune-mediated diseases- novel insights into underlying mechanisms and therapeutic approaches

Yuval Tal, Oded Shamriz, Irit Adini

Frontiers Media SA

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Immune-mediated disease,­immunology,­allergies,­Autoimmune,­disorder

Immune dysregulation as a critical driver of chronic inflammatory diseases

Rizgar A. Mageed, Voon Ong, David John Abraham, Richard Williams

Frontiers Media SA

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: immuneregulation,­Immunemetabolism,­Pathogenesis,­Inflammation,­Autoimmune Diseases,­Therapeutic perspectives

Autoimmune pre-disease

Ralf J. Ludwig, Jennifer Elisabeth Hundt, Kyle T. Amber, Markus H. Hoffmann

Frontiers Media SA

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Autoimmune pre-disease,­Disease,­biomarkers,­Autoantibody,­T cells