Achilles Heel of CAR T-Cell Therapy

Maurizio Chiriva-Internati, Fabio Grizzi

Frontiers Media SA

Chimeric Antigen Receptor (CAR) T-cell therapy represents a groundbreaking advancement in cancer...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: CAR-T therapy,­biomarker,­ag,­ab,­target,­Allogeneic,­autologous,­cell therapy,­virus,­innate and adoptive cell therapy

Animal-borne viral disease: Pathogenesis, Innate immunity, Acquired immunity, and Novel vaccine development

Lei Tan, Fulong Nan, Shen Yang

Frontiers Media SA

Currently, animal-borne viral diseases seriously threaten the development of the world's breeding...

Health Immunology Viral Immunology

Keywords: Animal-borne viral disease,­animal-borne infectious disease

Community Series in The Immunosuppressive Tumor Microenvironment and Strategies to Revert its Immune Regulatory Milieu for Cancer Immunotherapy, volume II

Jayakumar Nair, Mazdak Ganjalikhani Hakemi

Frontiers Media SA

This Research Topic is the second volume of the “The Immunosuppressive Tumor Microenvironment and...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Tumor Microenvironment,­Tumor immunotherapy,­immunosurveillance,­Immunometabolism,­Immunosuppressive cells,­Tumor spheroids,­tumor organoids,­Multiorgan-on-chip,­organ-on-chip,­Microfluidic chips

Host-Microbiota Immuno-Interactions for Personalized Microbial Therapeutics

Nar Singh Chauhan, Sunil Kumar Raghav, Shashank Gupta

Frontiers Media SA

Host-microbiota immuno-interactions are fundamental to immune regulation and the development of...

Health Immunology Mucosal Immunity

Keywords: microbiota,­Dysbiosis,­personalized,­Microbial,­Therapeutics,­Immune homeostasis,­tolerance,­Microbes

New Avenues for the Development of Advanced Immunotherapies: Capitalizing on Studies of the B and T Cell Receptor Repertoire

Massimiliano Mazza, Fabio Nicolini, Maria Del Mar Naranjo Gomez, Mireia Pelegrin

Frontiers Media SA

Immunotherapy has emerged as a transformative domain within oncology and a variety of other medical...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Antibody identification and engineering,­Immunotherapy,­bi-specific antibodies,­CAR-T cells,­TCR/ BCR repertoire study

The Role of Inflammation in Organ Injury

Xin Zhang, Di Fan, Lijun Cheng, Can Hu

Frontiers Media SA

Inflammation is implicated in the pathogenesis of various diseases, including cardiovascular,...

Health Immunology Inflammation

Keywords: Inflammation,­Organ injury,­Sepsis,­biomarkers,­Cytokines

Use of Big Data and Artificial Intelligence in Multiple Sclerosis

Hans-Peter Hartung, Liesbet M. Peeters, Giancarlo Comi, Axel Faes

Frontiers Media SA

Rapid advances in Artificial Intelligence (AI) and the growing health data volume are expected to...

Health Immunology Multiple Sclerosis and Neuroimmunology

Keywords: artificial intelligence,­Multiple Sclerosis,­Trustworthy AI,­Patient expectations

Response/Resistance to PD-1 Axis Inhibitors: Focus on the Tumor Microenvironment

Thazin N. Aung, Ioannis Vathiotis, Arutha Kulasinghe

Frontiers Media SA

PD-1 axis inhibitors are a group of immune checkpoint inhibitors (ICIs) that block the PD-1/PD-L1...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: PD-1 inhibitor,­Tumor Microenvironment,­Immunotherapy response,­resistance to PD-1 inhibitor,­PD-1/PD-L1 blockade,­cancer immunotherapy,­T cells,­NK cells,­Immunotherapy resistance

Community Series in Immune Responses Against Tumors - From the Bench to the Bedside, volume II

Tiezheng Hou, Xiaoxiao Liu, Chunjing Wang, Shisan Bao

Frontiers Media SA

This Research Topic is the second volume of the “Immune Responses Against Tumors - From the Bench...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: amino acid metabolism,­machine learning,­Clonal neoantigen,­adoptive cell therapy,­Targeted nanoparticle