Biology of Mesenchymal Stromal Cells -Emerging New Concepts to Improve Function and Scalability

Tokiko Nagamura-Inoue, Willem Fibbe, Keiya Ozawa

Frontiers Media SA

Human mesenchymal stromal cells (MSCs) can be harvested from many tissues, including bone marrow...

Science Cell and Developmental Biology Stem Cell Research

Keywords: Mesenchymal Stromal Cells,­Immunological regulation,­Tissue source,­Scalability,­genetic modification,­iPS cells,­Regenerative Medicine,­Host-derived factors,­platform for cancer therapy

Myc as a Disease Target Beyond Cancer

Jonathan R. Whitfield, Mariano F. Zacarias-Fluck, John Sedivy, Yulia A. Nevzorova, Jastrinjan Kaur

Frontiers Media SA

Myc is a pleiotropic transcription factor fundamental for many cellular processes. It is an...

Science Cell and Developmental Biology Signaling

Keywords: MYC,­therapy,­disease target,­non-cancerous conditions,­non-oncological pathologies,­Myc-related pathologies

Network-based Mathematical Modeling in Cell and Developmental Biology

Susan Mertins, Michael Blinov

Frontiers Media SA

The vast amount of knowledge in Cell Signaling gathered through reductionist efforts and omics...

Science Cell and Developmental Biology Signaling

Keywords: cellular reaction networks,­mathematical modelling,­math biology,­differential equations,­graph theory,­Boolean models,­whole cell modelling

Mitochondrial Plasticity and Quality Control in Health and Disease

Milena Rizzo, Francesca Forini, Emilia Bramanti, Elena Levantini, Filippo M. Santorelli, Azhar Ali, Vincenzo Lionetti

Frontiers Media SA

Mitochondria are essential cytosolic organelles that meet the rapidly-changing metabolic needs of...

Science Cell and Developmental Biology Cellular Biochemistry

Keywords: Mitochondrial plasticity,­Oxidative Stress,­mitochondria dysfunctions

In Celebration of Women in Molecular and Cellular Reproduction

Dolores Busso, Vanina Gabriela Da Ros, Patricia S. Cuasnicu

Frontiers Media SA

At present, less than 30% of researchers worldwide are women. Long-standing biases and gender...

Science Cell and Developmental Biology Molecular and Cellular Reproduction

Keywords: molecular reproduction,­cellular reproduction,­women in science,­Gender Equality