In the last decades bioactive glass has been used on studies about the specific effects on remineralization of dentin, due to their excellent regenerative properties in mineralized tissues. It is known that the effect of bioactive glass can be enhanced in the nanoscale. The incorporation of Fluor may result in formation of fluorapatite (FAP), which is chemically more stable than hydroxyapatite or carbonated hydroxyapatite, and therefore is of interest for dental applications. The aim of this study was to synthesize and characterize a new system of Fluor containing bioactive glass nanoparticles (BGNPF). As the synthesis of BGNPF by the sol gel route is a pioneer research, previous steps were necessary for the development of this work. Thus, this study initially evaluated bioactive glass microparticles containing different Fluorine contents, to finally synthesize and evaluate the Fluor containing bioactive glass nanoparticles. A sol-gel route assisted by ultrassound was used in the synthesis of BGNPF.
The particles obtained were characterized by Scanning Electron Microscopy (SEM), Energy dispersive spectroscopy (EDS), Atomic force microscopy (AFM), X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), Energy dispersive spectroscopy (EDS) and Dynamic Light Scattering (DLS), Brunauer-Emmett-Teller (BET), diffraction laser (Cilas) and X-ray photoelectron spectroscopy (XPS). SEM micrographs showed that the particles are quite uniform spherical nanostructures, occurring agglomeration or partial sinterization of the particulate system after heat treatment. XRD and XPS analysis are presented.
The results suggest the formation of fluorapatite crystals embedded within the matrix of the bioactive glass nanoparticles.
CNPq; CAPES; FAPEMIG
References:
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