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   Detailed Profile
Dr. Yoav Paas
Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Israel

Brief Biography
Dr. Paas undergraduated at the Tel-Aviv University (focusing on biochemistry). Then, he graduated at the Weizmann Institute of Science, Rehovot, Israel, where he earned a MSc degree for the work on the complement system (Dept. of Immunology), and a PhD degree for the work on brain ionotropic glutamate receptors (with Prof. Vivian I. Teichberg, Dept. of Neurobiology). Dr. Paas spent four years as a postdoctoral fellow in the laboratory of Prof. Jean-Pierre Changeux, Pasteur Institute, Paris, France and then got a position of Maitre de Conference (assistant professor) from the College de France. During his stay in France, Dr. Paas focused on structural studies of Cys-loop receptors, particularly the acetylcholine receptor. Following his return to Israel and after spending approximately a year as a visiting scientist at the Sackler School of Medicine, Tel-Aviv University (with Prof. Bernard Attali), Dr. Paas joined the Bar-Ilan University where he established a laboratory for Biophysics, Pharmacology and Structure of Ion Channels and serves as a senior lecturer. Major research achievements: 1. Identification and localization of an extracellular guanine nucleotide-binding site in brain ionotropic glutamate receptors. 2. Identification of all the amino acids that comprise the neurotransmitter-binding pocket of an ionotropic glutamate receptor. 3. Probing the closed and open pore conformations and the gating motions of the pore-lining helices of a Cys-loop receptor. 4. Identification and characterization of the mechanism of chloride selection by an invertebrate Cys-loop receptor that responds to glutamate. 5. Organization of acetylcholine receptor molecules in three-dimensional micrometer-sized crystals that are now being used as a source of seeds for epitaxial growth of larger crystals.

Education and Training
Postdoctoral Res. Fellow (Natural Sciences-Space Sciences)
Pasteur Institute, France
     
1996-2000



Ph.D (Natural Sciences-Space Sciences)
Weizmann Institute of Science (Dept. of Neuroscience), Israel
     
1991-1996



MSc (Natural Sciences-Life Sciences)
Weizmann Institute of Science (Dept. of Immunology), Israel
     
1987-1990



B.S. in Biology
Faculty of Life Sciences, Tel Aviv University, Israel
     
1987-




Positions and Experience
Senior Lecturer & Research Group Leader
Bar-Ilan University (The Mina and Everard Goodman Faculty of Life Sciences)Israel
2006



Visiting scientist
Tel-Aviv University (Sackler Faculty of Medicine)Israel
2004-2006



Assistant Professor
Pasteur Institute/Collége de FranceFrance
2000-2003




Honours and Awards
Awarded grant for establishing a new laboratory
Natural Sciences - Space Sciences
Wolfson Family Foundation
2007



Awarded personal research grant
Natural Sciences - Space Sciences
Israel Science Foundation
2007



Long-term (postdoctoral) fellowship
Natural Sciences - Space Sciences
Federation of European Biochemical Societies (FEBS)
1997



Long-term (postdoctoral) fellowship
Natural Sciences - Space Sciences
Human Frontier Science Program Organization (HFSPO)
1997



Manlio Cantarini postdoctoral fellowship
Natural Sciences - Space Sciences
Pasteur Institute, Paris
1966




Affiliation
Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University
Israel, 52900