Original Research Article
The Neuroterrain 3D Mouse Brain Atlas
Drexel University College of Medicine, USA
A significant objective of neuroinformatics is the construction of tools to readily access, search, and analyze anatomical imagery. This goal can be subdivided into development of the necessary databases and of the computer vision tools for image analysis. When considering mesoscale images, the latter tools can be further divided into registration algorithms and anatomical models. The models are atlases that contain both bitmap images and templates of anatomical boundaries. We report here on construction of such a model for the C57BL/6J mouse. The intended purpose of this atlas is to aid in automated segmentation of the Mouse Brain Library, a database of brain histological images of importance to neurogenetic research.
Keywords: atlas, 3D reconstruction, brain model, automated segmentation, neuroanatomy, spatial normalization, standard coordinate space, registration
Copyright: © Bertrand and Nissanov. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
*Correspondence: Jonathan Nissanov, Department of Neurobiology & Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA. jonathan.nissanov@drexelmed.edu
Received: 05 March 2008; paper pending published: 17 April 2008;
Edited by:
Maryann E. Martone, University of California San Diego, USA
*Correspondence: Jonathan Nissanov, Department of Neurobiology & Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA. jonathan.nissanov@drexelmed.edu
