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Published on 19 Jun 2024

Ultrasound beam triggers ‘nanodroplets' to deliver drugs at exactly the right spot

Conventional drug delivery is inefficient and imprecise. Through a series of preclinical experiments, researchers from the University of Utah have optimized a novel, targeted method of delivery through nanodroplet carriers, which are triggered to release their drug at exactly the desired spot by a focused beam of ultrasound. Their results showed that nanodroplets with a core of perfluorooctylbromide are stable, efficient in delivery, and well tolerated. Clinical experiments are likely to follow.

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Published on 25 Jun 2024

Internet for billions in 100 countries with no current access and hope for transplant patients worldwide in new World Economic Forum emerging technologies report

The World Economic Forum, in association with Frontiers, new Top 10 Emerging Technologies of 2024, released today (25 June), shows that among technologies emerging globally, reconfigurable intelligent surfaces and High-Altitude Platform Systems have the potential to connect billions worldwide who currently have no internet access.

Frontiers news

Published on 19 Jun 2024

Mia Strand - A spotlight on arts-based research towards equitable oceans

Dr Mia Strand is a postdoctoral research fellow with Ocean Nexus, a research institute which conducts ocean equity research, and is based at the Institute for Coastal and Marine Research at Nelson Mandela University in South Africa. She is also a co-investigator on the international research program One Ocean Hub, based out of Strathclyde University in Scotland. Her research focuses specifically on equity in knowledge co-production processes, ocean literacies, and children’s rights to a healthy ocean, and centers around arts-based research methods, such as photo stories and storytelling. Representing South Africa, Mia is one of the 23 National Champions in line for the 2024 Frontiers Planet Prize. Our oceans are currently in a state of emergency with ocean heat at record levels causing events such as ocean acidification and coral bleaching. Maintaining the health of our oceans is key to ensuring that we do not cross the limits of the nine planetary boundaries. In line with World Ocean Day and SDG14 (Life Below Water), we spoke to Mia about changing the way we develop and promote ocean knowledge and ocean literacies, and how arts-based methods can bridge the gap between traditional sciences and local knowledge systems.

Health

Published on 19 Jun 2024

Ultrasound beam triggers ‘nanodroplets' to deliver drugs at exactly the right spot

Conventional drug delivery is inefficient and imprecise. Through a series of preclinical experiments, researchers from the University of Utah have optimized a novel, targeted method of delivery through nanodroplet carriers, which are triggered to release their drug at exactly the desired spot by a focused beam of ultrasound. Their results showed that nanodroplets with a core of perfluorooctylbromide are stable, efficient in delivery, and well tolerated. Clinical experiments are likely to follow.

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Published on 11 Jun 2024

How older people explore new spaces could suggest cognitive decline and dementia

Aging people commonly show a decline in navigation ability, and this has generally been attributed to worsening spatial memory. But now, researchers from the US have shown for the first time that this decline is partly driven by changes in typical exploration behavior by middle age. In a maze learning task, middle-aged people were less efficient explorers than young people. This discovery could have applications in the clinical diagnosis and therapy of cognitive decline and dementia.

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