Dietary calcium intake in post-menopausal women in the metabolic bone clinic: assessment of requirement for calcium-containing supplements
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1
Guy's Hospital, Osteoporosis Clinic, Rheumatology, United Kingdom
Most guidelines recommend adequate calcium and vitamin D intake as part of prevention and treatment for osteoporosis. Calcium and vitamin D supplements are routinely prescribed as adjunct to bisphosphonate therapy. Concerns have been raised, recently, following reports of an increased risk of myocardial infarction in women given calcium supplementation. In contrast, epidemiological studies do not show increased cardiovascular risks with higher dietary calcium intake. In order to ascertain the need for calcium supplements, we assessed the dietary calcium intake of post-menopausal women attending the osteoporosis clinic and the prevalence of cardiovascular risk factors in this population. We studied 118 women aged mean [SD] 67[13] years. Seventy one (60%) were on bisphosphonates and 41 (34%) had a previous fragility fracture. Calcium intake was assessed by dietary recall on 2 consecutive days and calculated using a calcium intake calculator. The presence of cardiovascular risk factors which included ischaemic/cardiovascular disease (IHD/CVD), hypertension, hyperlipidaemia was recorded. The subjects were divided in quartiles based on their dietary calcium intake (Group 1 : 0-400 mg/day, Group 2 : 401-800 mg/day, Group 3 : 801-1200 mg/day, Group 4 : >1200 mg/day). Thirty eight women (32%) had a dietary calcium intake of greater than 800 mg/day (Group 3) and 41 (35%) had a dietary intake of greater than 1200 mg (Group 4). In Group 3, the number of patients with a history of IHD/CVD was 22 (58%), hypertension 15 (39%) and hyperlipidaemia 11 (29%). In Group 4, the numbers were as follows;IHD/CVD: 17 (41%), hypertension: 15 (37%), hyperlipidaemia: 5(12%). Many patients receiving bisphosphonates will be prescribed 1200 mg of calcium and 800 IU vitamin D. In view of recent concerns, reduced dosage of calcium supplements should be considered, depending on dietary calcium intake, particularly in the elderly.
Keywords:
Bones,
Bone Research
Conference:
2011 joint meeting of the Bone Research Society & the British Orthopaedic Research Society, Cambridge, United Kingdom, 27 Jun - 29 Jun, 2011.
Presentation Type:
Poster
Topic:
Abstracts
Citation:
Chotai
A,
Satkunananthan
L,
Inaoui
R,
Fogelman
I and
Hampson
G
(2011). Dietary calcium intake in post-menopausal women in the metabolic bone clinic: assessment of requirement for calcium-containing supplements.
Front. Endocrinol.
Conference Abstract:
2011 joint meeting of the Bone Research Society & the British Orthopaedic Research Society.
doi: 10.3389/conf.fendo.2011.02.00010
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Received:
30 Sep 2011;
Published Online:
30 Sep 2011.
*
Correspondence:
Mr. A Chotai, Guy's Hospital, Osteoporosis Clinic, Rheumatology, London, W6 8LH, United Kingdom, amar.chotai@kcl.ac.uk